Literature DB >> 22105147

Role of the recently identified dysadherin in E-cadherin adhesion molecule downregulation in head and neck cancer.

Alexandros Georgolios1, Anna Eleftheriadou, Anna Batistatou, Kostandinos Charalabopoulos.   

Abstract

Dysadherin is a cancer-related cell membrane glycoprotein, recently identified, playing an important role in tumor progression and metastasis. In the present minireview article, we are focusing on the role of dysadherin in E-cadherin downregulation, the various expression patterns of the molecule in head and neck cancer as well as its potential role as a molecular target for future applications in diagnosis, clinical routine and prognosis of the disease.

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Year:  2011        PMID: 22105147     DOI: 10.1007/s12032-011-0118-3

Source DB:  PubMed          Journal:  Med Oncol        ISSN: 1357-0560            Impact factor:   3.064


  46 in total

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Journal:  J Thorac Cardiovasc Surg       Date:  2005-09       Impact factor: 5.209

Review 2.  Role and expression patterns of E-cadherin in head and neck squamous cell carcinoma (HNSCC).

Authors:  A Georgolios; A Batistatou; L Manolopoulos; K Charalabopoulos
Journal:  J Exp Clin Cancer Res       Date:  2006-03

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Authors:  A Mitselou; E Ioachim; D Peschos; K Charalabopoulos; M Michael; N J Agnantis; T Vougiouklakis
Journal:  Exp Oncol       Date:  2007-03

4.  E-cadherin is a selective and strongly dominant prognostic factor in squamous cell carcinoma: a comparison of E-cadherin with desmosomal components.

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Journal:  Int J Cancer       Date:  2005-05-01       Impact factor: 7.396

5.  Prognostic significance of dysadherin expression in tongue cancer: immunohistochemical analysis of 91 cases.

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Journal:  Appl Immunohistochem Mol Morphol       Date:  2004-12

6.  Role of E-cadherins in development of lymphatic tumor emboli.

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Journal:  Cancer       Date:  2003-05-01       Impact factor: 6.860

7.  Clinicopathologic significance of dysadherin expression in cutaneous malignant melanoma: immunohistochemical analysis of 115 patients.

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Journal:  Cancer       Date:  2005-04-15       Impact factor: 6.860

Review 8.  Inactivation of the E-cadherin-mediated cell adhesion system in human cancers.

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9.  Dysadherin expression in gastrointestinal stromal tumors (GISTs).

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Journal:  Pathol Res Pract       Date:  2009-02-12       Impact factor: 3.250

10.  In breast carcinoma dysadherin expression is correlated with invasiveness but not with E-cadherin.

Authors:  A Batistatou; D Peschos; H Tsanou; A Charalabopoulos; Y Nakanishi; S Hirohashi; N J Agnantis; K Charalabopoulos
Journal:  Br J Cancer       Date:  2007-04-17       Impact factor: 7.640

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4.  Prognostic value of dysadherin in cancer: A systematic review and meta-analysis.

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