M Swart1, J B Carlisle. 1. Department of Anaesthesia and Critical Care Medicine, Torbay Hospital, Torquay TQ2 7AA, UK. michael.swart@nhs.net
Abstract
BACKGROUND: Evidence for the benefit of critical care after surgery is limited. This study assessed the value of immediate admission to the critical care unit (CCU) after open colorectal surgery. METHODS: Patients aged over 45 years were screened with a cardiopulmonary exercise test to determine their anaerobic threshold. Less fit patients defined by an anaerobic threshold below 11 ml oxygen per kg per min were assigned to either critical care or surgical ward care. Those with an anaerobic threshold of 11 ml oxygen per kg per min or above were assigned to ward care. The outcome measure was the number of cardiac events. RESULTS: Of 153 patients who underwent exercise testing, 55 had an anaerobic threshold of at least 11 ml oxygen per kg per min (ward care) and 98 had a threshold of less than 11 ml oxygen per kg per min, of whom 39 were allocated to ward care and 51 to critical care. Median length of CCU stay was 31 (range 5-46) h. More cardiac events occurred in patients allocated to ward care (7 of 39) than in those allocated to critical care (0 of 51): absolute difference 18 (95 per cent confidence interval 10 to 26) per cent (P = 0·002). There were no cardiac events in patients with an anaerobic threshold of 11 ml oxygen per kg per min or higher. CONCLUSION: Patients with an anaerobic threshold of at least 11 ml oxygen per kg per min and those with a threshold below 11 ml oxygen per kg per min managed in the CCU had fewer cardiac events.
BACKGROUND: Evidence for the benefit of critical care after surgery is limited. This study assessed the value of immediate admission to the critical care unit (CCU) after open colorectal surgery. METHODS:Patients aged over 45 years were screened with a cardiopulmonary exercise test to determine their anaerobic threshold. Less fit patients defined by an anaerobic threshold below 11 ml oxygen per kg per min were assigned to either critical care or surgical ward care. Those with an anaerobic threshold of 11 ml oxygen per kg per min or above were assigned to ward care. The outcome measure was the number of cardiac events. RESULTS: Of 153 patients who underwent exercise testing, 55 had an anaerobic threshold of at least 11 ml oxygen per kg per min (ward care) and 98 had a threshold of less than 11 ml oxygen per kg per min, of whom 39 were allocated to ward care and 51 to critical care. Median length of CCU stay was 31 (range 5-46) h. More cardiac events occurred in patients allocated to ward care (7 of 39) than in those allocated to critical care (0 of 51): absolute difference 18 (95 per cent confidence interval 10 to 26) per cent (P = 0·002). There were no cardiac events in patients with an anaerobic threshold of 11 ml oxygen per kg per min or higher. CONCLUSION:Patients with an anaerobic threshold of at least 11 ml oxygen per kg per min and those with a threshold below 11 ml oxygen per kg per min managed in the CCU had fewer cardiac events.
Authors: Pervez Sultan; Mark R Edwards; Ana Gutierrez del Arroyo; David Cain; J Robert Sneyd; Richard Struthers; Gary Minto; Gareth L Ackland Journal: Mediators Inflamm Date: 2014-06-26 Impact factor: 4.711
Authors: Morten Vester-Andersen; Tina Waldau; Jørn Wetterslev; Morten Hylander Møller; Jacob Rosenberg; Lars Nannestad Jørgensen; Inger Gillesberg; Henrik Loft Jakobsen; Egon Godthåb Hansen; Lone Musaeus Poulsen; Jan Skovdal; Ellen Kristine Søgaard; Morten Bestle; Jesper Vilandt; Iben Rosenberg; Rasmus Ehrenfried Berthelsen; Jens Pedersen; Mogens Rørbæk Madsen; Thomas Feurstein; Malene Just Busse; Johnny D H Andersen; Christian Maschmann; Morten Rasmussen; Christian Jessen; Lasse Bugge; Helle Ørding; Ann Merete Møller Journal: Trials Date: 2013-02-02 Impact factor: 2.279