Literature DB >> 22101272

TFEB, a novel mTORC1 effector implicated in lysosome biogenesis, endocytosis and autophagy.

Samuel Peña-Llopis, James Brugarolas.   

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Year:  2011        PMID: 22101272      PMCID: PMC3272281          DOI: 10.4161/cc.10.23.18251

Source DB:  PubMed          Journal:  Cell Cycle        ISSN: 1551-4005            Impact factor:   4.534


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  11 in total

1.  Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways.

Authors:  Michela Palmieri; Soren Impey; Hyojin Kang; Alberto di Ronza; Carl Pelz; Marco Sardiello; Andrea Ballabio
Journal:  Hum Mol Genet       Date:  2011-07-13       Impact factor: 6.150

2.  Activation of a metabolic gene regulatory network downstream of mTOR complex 1.

Authors:  Katrin Düvel; Jessica L Yecies; Suchithra Menon; Pichai Raman; Alex I Lipovsky; Amanda L Souza; Ellen Triantafellow; Qicheng Ma; Regina Gorski; Stephen Cleaver; Matthew G Vander Heiden; Jeffrey P MacKeigan; Peter M Finan; Clary B Clish; Leon O Murphy; Brendan D Manning
Journal:  Mol Cell       Date:  2010-07-30       Impact factor: 17.970

Review 3.  mTOR: from growth signal integration to cancer, diabetes and ageing.

Authors:  Roberto Zoncu; Alejo Efeyan; David M Sabatini
Journal:  Nat Rev Mol Cell Biol       Date:  2010-12-15       Impact factor: 94.444

4.  Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake.

Authors:  Aimee L Edinger; Craig B Thompson
Journal:  Mol Biol Cell       Date:  2002-07       Impact factor: 4.138

5.  mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.

Authors:  Pradip K Majumder; Phillip G Febbo; Rachel Bikoff; Raanan Berger; Qi Xue; Louis M McMahon; Judith Manola; James Brugarolas; Timothy J McDonnell; Todd R Golub; Massimo Loda; Heidi A Lane; William R Sellers
Journal:  Nat Med       Date:  2004-05-23       Impact factor: 53.440

6.  TSC2 regulates VEGF through mTOR-dependent and -independent pathways.

Authors:  James B Brugarolas; Francisca Vazquez; Archana Reddy; William R Sellers; William G Kaelin
Journal:  Cancer Cell       Date:  2003-08       Impact factor: 31.743

7.  Termination of autophagy and reformation of lysosomes regulated by mTOR.

Authors:  Li Yu; Christina K McPhee; Lixin Zheng; Gonzalo A Mardones; Yueguang Rong; Junya Peng; Na Mi; Ying Zhao; Zhihua Liu; Fengyi Wan; Dale W Hailey; Viola Oorschot; Judith Klumperman; Eric H Baehrecke; Michael J Lenardo
Journal:  Nature       Date:  2010-06-06       Impact factor: 49.962

8.  Transcriptional activation of lysosomal exocytosis promotes cellular clearance.

Authors:  Diego L Medina; Alessandro Fraldi; Valentina Bouche; Fabio Annunziata; Gelsomina Mansueto; Carmine Spampanato; Claudia Puri; Antonella Pignata; Jose A Martina; Marco Sardiello; Michela Palmieri; Roman Polishchuk; Rosa Puertollano; Andrea Ballabio
Journal:  Dev Cell       Date:  2011-09-01       Impact factor: 12.270

9.  Regulation of TFEB and V-ATPases by mTORC1.

Authors:  Samuel Peña-Llopis; Silvia Vega-Rubin-de-Celis; Jacob C Schwartz; Nicholas C Wolff; Tram Anh T Tran; Lihua Zou; Xian-Jin Xie; David R Corey; James Brugarolas
Journal:  EMBO J       Date:  2011-07-29       Impact factor: 11.598

10.  SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth.

Authors:  Thomas Porstmann; Claudio R Santos; Beatrice Griffiths; Megan Cully; Mary Wu; Sally Leevers; John R Griffiths; Yuen-Li Chung; Almut Schulze
Journal:  Cell Metab       Date:  2008-09       Impact factor: 27.287

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  18 in total

1.  Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1.

Authors:  Tianyi Zhang; Qingxiang Zhou; Margret Helga Ogmundsdottir; Katrin Möller; Robert Siddaway; Lionel Larue; Michael Hsing; Sek Won Kong; Colin Ronald Goding; Arnar Palsson; Eirikur Steingrimsson; Francesca Pignoni
Journal:  J Cell Sci       Date:  2015-06-19       Impact factor: 5.285

2.  Multistep regulation of TFEB by MTORC1.

Authors:  Silvia Vega-Rubin-de-Celis; Samuel Peña-Llopis; Meghan Konda; James Brugarolas
Journal:  Autophagy       Date:  2017-01-05       Impact factor: 16.016

3.  TLR4 activation under lipotoxic conditions leads to synergistic macrophage cell death through a TRIF-dependent pathway.

Authors:  Joel D Schilling; Heather M Machkovech; Li He; Abhinav Diwan; Jean E Schaffer
Journal:  J Immunol       Date:  2012-12-28       Impact factor: 5.422

4.  α-Fucosidase as a novel convenient biomarker for cellular senescence.

Authors:  Dominic G Hildebrand; Simon Lehle; Andreas Borst; Sebastian Haferkamp; Frank Essmann; Klaus Schulze-Osthoff
Journal:  Cell Cycle       Date:  2013-05-13       Impact factor: 4.534

Review 5.  Chaperone-mediated autophagy: roles in neurodegeneration.

Authors:  Gang Wang; Zixu Mao
Journal:  Transl Neurodegener       Date:  2014-09-21       Impact factor: 8.014

Review 6.  Disorders of lysosomal acidification-The emerging role of v-ATPase in aging and neurodegenerative disease.

Authors:  Daniel J Colacurcio; Ralph A Nixon
Journal:  Ageing Res Rev       Date:  2016-05-16       Impact factor: 10.895

Review 7.  The Drosophila Accessory Gland as a Model for Prostate Cancer and Other Pathologies.

Authors:  C Wilson; A Leiblich; D C I Goberdhan; F Hamdy
Journal:  Curr Top Dev Biol       Date:  2016-07-25       Impact factor: 4.897

8.  Mechanistic or mammalian target of rapamycin (mTOR) may determine robustness in young male mice at the cost of accelerated aging.

Authors:  Olga V Leontieva; Geraldine M Paszkiewicz; Mikhail V Blagosklonny
Journal:  Aging (Albany NY)       Date:  2012-12       Impact factor: 5.682

9.  Induction of autophagy-dependent cell death by the survivin suppressant YM155 in salivary adenoid cystic carcinoma.

Authors:  Yu-Fan Wang; Wei Zhang; Ke-Fei He; Bing Liu; Lu Zhang; Wen-Feng Zhang; Ashok B Kulkarni; Yi-Fang Zhao; Zhi-Jun Sun
Journal:  Apoptosis       Date:  2014-04       Impact factor: 5.561

10.  Translocational renal cell carcinoma (t(6;11)(p21;q12) with transcription factor EB (TFEB) amplification and an integrated precision approach: a case report.

Authors:  Wolfgang Lilleby; Ljiljana Vlatkovic; Leonardo A Meza-Zepeda; Mona-Elisabeth Revheim; Eivind Hovig
Journal:  J Med Case Rep       Date:  2015-12-09
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