Literature DB >> 22100313

aza-Flavanones as potent cross-species microRNA inhibitors that arrest cell cycle.

Srivari Chandrasekhar1, Sreerangam N C V L Pushpavalli, Srinivas Chatla, Debasmita Mukhopadhyay, Bogonda Ganganna, Kandi Vijeender, Pabbaraja Srihari, Chada Raji Reddy, M Janaki Ramaiah, Utpal Bhadra.   

Abstract

aza-Flavanones have been identified as a new class of selective microRNA inhibitors. These compounds were found to arrest cell cycle via a novel cross species microRNA-dependent regulatory pathway interpreting an unexpected link between cell cycle arrest and microRNA mediated control in cancer.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 22100313     DOI： 10.1016/j.bmcl.2011.10.061

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  9 in total

1.  Synthesis, molecular modeling and biological evaluation of aza-flavanones as α-glucosidase inhibitors.

Authors:  Sivaprasad Kasturi; Sujatha Surarapu; Chandra Chary Bathoju; Srinivas Uppalanchi; Shubham Dwivedi; Yogeeswari Perumal; Dilep Kumar Sigalapalli; Bathini Nagendra Babu; Krishna S Ethiraj; Jaya Shree Anireddy
Journal:  Medchemcomm       Date:  2017-06-14       Impact factor: 3.597

Review 2.  Small molecule compounds targeting miRNAs for cancer therapy.

Authors:  Paloma Del C Monroig; Lu Chen; Shuxing Zhang; George A Calin
Journal:  Adv Drug Deliv Rev       Date:  2014-09-17       Impact factor: 15.470

Review 3.  Structure based approaches for targeting non-coding RNAs with small molecules.

Authors:  Matthew D Shortridge; Gabriele Varani
Journal:  Curr Opin Struct Biol       Date:  2015-02-16       Impact factor: 6.809

4.  Synthesis and X-ray study of dispiro 8-nitroquinolone analogues and their cytotoxic properties against human cervical cancer HeLa cells.

Authors:  Selvaraj Shyamsivappan; Raju Vivek; Arjunan Saravanan; Thangaraj Arasakumar; Gopalan Subashini; Thangaraj Suresh; Ramasamy Shankar; Palathurai Subramaniam Mohan
Journal:  Medchemcomm       Date:  2019-01-22       Impact factor: 3.597

5.  HDAC inhibitor misprocesses bantam oncomiRNA, but stimulates hid induced apoptotic pathway.

Authors:  Utpal Bhadra; Tanmoy Mondal; Indira Bag; Debasmita Mukhopadhyay; Paromita Das; Bibhuti B Parida; Prathama S Mainkar; Chada Raji Reddy; Manika Pal Bhadra
Journal:  Sci Rep       Date:  2015-10-07       Impact factor: 4.379

Review 6.  Recent syntheses of 1,2,3,4-tetrahydroquinolines, 2,3-dihydro-4(1H)-quinolinones and 4(1H)-quinolinones using domino reactions.

Authors:  Baskar Nammalwar; Richard A Bunce
Journal:  Molecules       Date:  2013-12-24       Impact factor: 4.411

7.  Synthesis and photophysical properties of 2-aryl-6,8-bis(arylethenyl)-4-methoxyquinolines.

Authors:  Tebogo Ankie Khoza; Marole Maria Maluleka; Neliswa Mama; Malose Jack Mphahlele
Journal:  Molecules       Date:  2012-11-30       Impact factor: 4.411

8.  Identification of miRNA-Small Molecule Associations by Continuous Feature Representation Using Auto-Encoders.

Authors:  Ibrahim Abdelbaky; Hilal Tayara; Kil To Chong
Journal:  Pharmaceutics       Date:  2021-12-21       Impact factor: 6.321

Review 9.  Noncoding RNA therapeutics - challenges and potential solutions.

Authors:  Melanie Winkle; Sherien M El-Daly; Muller Fabbri; George A Calin
Journal:  Nat Rev Drug Discov       Date:  2021-06-18       Impact factor: 84.694
  9 in total

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