Literature DB >> 22098172

Convergent formal synthesis of (±)-roseophilin.

Chuanjun Song1, Hui Liu, Meiling Hong, Yuanyuan Liu, Feifei Jia, Li Sun, Zhenliang Pan, Junbiao Chang.   

Abstract

A facile convergent synthesis of the tricyclic core 2 of roseophilin is described, which represents the shortest route so far for the formal synthesis of roseophilin. The key step was a tandem pyrrole acylation-Nazarov cyclization reaction to form the cyclopenta[b]pyrrole moiety 4.

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Year:  2011        PMID: 22098172     DOI: 10.1021/jo201949x

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

1.  Modular access to complex prodiginines: total synthesis of (+)-roseophilin via its 2-azafulvene prototropisomer.

Authors:  James H Frederich; Patrick G Harran
Journal:  J Am Chem Soc       Date:  2013-03-01       Impact factor: 15.419

  1 in total

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