INTRODUCTION: Pure squamous cell carcinoma of the breast [SCCB] is rare. PRESENTATION OF CASE: We report a case of primary squamous cell carcinoma of breast with ipsilateral axillary lymph node metastasis in a 58year old woman. DISCUSSION: It is a breast carcinoma entirely composed of metaplastic squamous cells that may be keratinized, non-keratinized or spindled. The pure squamous cell carcinoma usually present with central cystic cavity, which we found in our case, also supported by immunohistochemical evidence. CONCLUSION: Although a rare breast cancer subtype, SCCB is of considerable interest due to its pathological heterogeneity and differences in clinical behavior and less reported occurrence of nodal metastasis.
INTRODUCTION: Pure squamous cell carcinoma of the breast [SCCB] is rare. PRESENTATION OF CASE: We report a case of primary squamous cell carcinoma of breast with ipsilateral axillary lymph node metastasis in a 58year old woman. DISCUSSION: It is a breast carcinoma entirely composed of metaplastic squamous cells that may be keratinized, non-keratinized or spindled. The pure squamous cell carcinoma usually present with central cystic cavity, which we found in our case, also supported by immunohistochemical evidence. CONCLUSION: Although a rare breast cancer subtype, SCCB is of considerable interest due to its pathological heterogeneity and differences in clinical behavior and less reported occurrence of nodal metastasis.
Authors: Bryan T Hennessy; Savitri Krishnamurthy; Sharon Giordano; Thomas A Buchholz; Shu W Kau; Zhigang Duan; Vicente Valero; Gabriel N Hortobagyi Journal: J Clin Oncol Date: 2005-11-01 Impact factor: 44.544
Authors: Annette Breuer; Michaela Kandel; Annette Fisseler-Eckhoff; Christian Sutter; Eva Schwaab; Hans-Joachim Lück; Andreas du Bois Journal: Onkologie Date: 2007-05-29
Authors: C Punzo; F Fortarezza; V De Ruvo; M Minafra; R Laforgia; G Casamassina; F Pezzuto; A Punzi; C Caporusso; G Angelelli; N Palasciano Journal: G Chir Date: 2017 May-Jun