Literature DB >> 22096700

Gastrointestinal stromal tumor of the stomach in a child with a 3-year follow-up period-Case report.

Marcelo Eller Miranda1, Luiz Ronaldo Alberti, Edson Samesima Tatsuo, Clécio Piçarro, Marcelo Rausch.   

Abstract

We report a case of a nine-year-old boy with a 4-week history of general fatigue, loss of appetite, vomits and hematemesis. Laboratory evaluation revealed a hemoglobin level of 4.4 g/dl. After a transfusion of packed red blood cells the patient underwent an esophagogastroduodenoscopy, which showed a smooth, rounded 6-8 cm submucosal lesion with a central depression with ulceration and active bleeding in the cardia extending to the fundus.Computed tomography (CT) of the chest, abdomen and pelvis showed a large mass originating from the gastric wall but not infiltrating surrounding organs, approximately 8.0 cm × 7.0 cm × 5 cm. Despite the tumor size, no metastases were diagnosed. The patient underwent a total gastrectomy in an en-bloc resection including the distal part of the esophagus (3 cm) and omentum with oncologic margins. Reconstruction was performed with a mediastinal end-to-side esophago-jejunal anastomosis. Immunehistochemic confirmed GIST. He remains well without evidence of disease after 36 months of follow-up with a multiprofessional team.

Entities:  

Keywords:  Abdominal tumor; Children; Diagnosis; Gastric; Gastrointestinal bleeding; Gastrointestinal stromal tumor; Submucosal tumors; c-KIT

Year:  2011        PMID: 22096700      PMCID: PMC3199713          DOI: 10.1016/j.ijscr.2011.02.010

Source DB:  PubMed          Journal:  Int J Surg Case Rep        ISSN: 2210-2612


  7 in total

1.  Multifocal gastrointestinal stromal tumor (GIST) of the stomach in an 11-year-old girl.

Authors:  Jin Park; Tara C Rubinas; Lynn Ansley Fordham; J Duncan Phillips
Journal:  Pediatr Radiol       Date:  2006-09-13

2.  Multiple gastric stromal tumors in a child without syndromic association lacks common KIT or PDGFRalpha mutations.

Authors:  Maureen J O'Sullivan; Amanda McCabe; Peter Gillett; Iain D Penman; Gordon A MacKinlay; Jon Pritchard
Journal:  Pediatr Dev Pathol       Date:  2005-11-18

Review 3.  Gastrointestinal stromal tumors in children and young adults: a clinicopathologic, molecular, and genomic study of 15 cases and review of the literature.

Authors:  Sonam Prakash; Lisa Sarran; Nicholas Socci; Ronald P DeMatteo; Jonathan Eisenstat; Alba M Greco; Robert G Maki; Leonard H Wexler; Michael P LaQuaglia; Peter Besmer; Cristina R Antonescu
Journal:  J Pediatr Hematol Oncol       Date:  2005-04       Impact factor: 1.289

Review 4.  Gastrointestinal stromal tumor in a child and review of the literature.

Authors:  Yutaka Hayashi; Tadaharu Okazaki; Atsuyuki Yamataka; Toshihiro Yanai; Yuichiro Yamashiro; Masahiko Tsurumaru; Yoshiaki Kajiyama; Takeshi Miyano
Journal:  Pediatr Surg Int       Date:  2005-11       Impact factor: 1.827

5.  Gastrointestinal stromal tumors of the stomach in children and young adults: a clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases with long-term follow-up and review of the literature.

Authors:  Markku Miettinen; Jerzy Lasota; Leslie H Sobin
Journal:  Am J Surg Pathol       Date:  2005-10       Impact factor: 6.394

6.  Gastrointestinal stromal tumors arising from the stomach: a report of three children.

Authors:  Megan M Durham; Kenneth W Gow; Bahig M Shehata; Howard M Katzenstein; Robert L Lorenzo; Richard R Ricketts
Journal:  J Pediatr Surg       Date:  2004-10       Impact factor: 2.545

7.  The endoscopic appearance of a gastrointestinal stromal tumor in a pediatric patient.

Authors:  Pramodha Muniyappa; Marsha Kay; Lisa Feinberg; Lori Mahajan; Anthony Stallion; Robert Wyllie
Journal:  J Pediatr Surg       Date:  2007-07       Impact factor: 2.545

  7 in total
  4 in total

1.  Incidental GIST after appendectomy in a pediatric patient: a first instance and review of pediatric patients with CD117 confirmed GISTs.

Authors:  Sifrance Tran; Michael Dingeldein; Sarah C Mengshol; Saundra Kay; Anthony C Chin
Journal:  Pediatr Surg Int       Date:  2013-11-30       Impact factor: 1.827

2.  Acute intestinal obstruction revealing synchronous gastrointestinal stromal tumors in a small bowel diverticulum and mucinous adenocarcinoma of the colon: a case report.

Authors:  El Ochi Mohamed Reda; Jahid Ahmed; El Ktaibi Abderrahim; Znati Kawtar; Zouaidia Fouad; Bernoussi Zakia; Mahassini Najat
Journal:  Pan Afr Med J       Date:  2015-07-02

3.  Life-threatening bleeding of a duodenal gastrointestinal stromal tumor in a teenager: a rare case report.

Authors:  Piero V Valli; Carlo Valli; Thomas Pfammatter; Peter Bauerfeind
Journal:  Endosc Int Open       Date:  2016-11-10

Review 4.  Extragastrointestinal stromal tumor of the mesoappendix: CT findings and a review of the literature.

Authors:  Wenhua Li; Yanfen Cui; Gang Ren; Jun Wang; Xiangru Wu
Journal:  World J Surg Oncol       Date:  2012-10-07       Impact factor: 2.754

  4 in total

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