Literature DB >> 22096254

Gene mutation and AML pathogenesis.

Hervé Dombret1.   

Abstract

In their large study of 1185 patients with acute myeloid leukemia (AML), Shen and colleagues have dissected the overlapping incidences and prognostic significances of mutations of the 12 genes most frequently mutated in AML,including FLT3, NPM1, CEBPA, KIT, N-RAS, MLL, WT1, IDH1/2, TET2, DNMT3A, and ASXL1.

Entities:  

Year:  2011        PMID： 22096254     DOI： 10.1182/blood-2011-09-379081

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  18 in total

Review 1.  Minimal residual disease in acute myelogenous leukemia.

Authors:  N M Cruz; N Mencia-Trinchant; D C Hassane; M L Guzman
Journal:  Int J Lab Hematol       Date:  2017-05       Impact factor: 2.877

2.  Genome-wide methylation profiling in decitabine-treated patients with acute myeloid leukemia.

Authors:  Pearlly Yan; David Frankhouser; Mark Murphy; Hok-Hei Tam; Benjamin Rodriguez; John Curfman; Michael Trimarchi; Susan Geyer; Yue-Zhong Wu; Susan P Whitman; Klaus Metzeler; Alison Walker; Rebecca Klisovic; Samson Jacob; Michael R Grever; John C Byrd; Clara D Bloomfield; Ramiro Garzon; William Blum; Michael A Caligiuri; Ralf Bundschuh; Guido Marcucci
Journal:  Blood       Date:  2012-07-11       Impact factor: 22.113

3.  A panoramic view of acute myeloid leukemia.

Authors:  Sai-Juan Chen; Yang Shen; Zhu Chen
Journal:  Nat Genet       Date:  2013-06       Impact factor: 38.330

4.  Accumulation of FLT3(+) CD11c (+) dendritic cells in psoriatic lesions and the anti-psoriatic effect of a selective FLT3 inhibitor.

Authors:  Heng-Xiu Yan; Wei-Wei Li; Yan Zhang; Xia-Wei Wei; Li-Xin Fu; Guo-Bo Shen; Tao Yin; Xiu-Ying Li; Hua-Shan Shi; Yang Wan; Qing-Yin Zhang; Jiong Li; Sheng-Yong Yang; Yu-Quan Wei
Journal:  Immunol Res       Date:  2014-10       Impact factor: 2.829

5.  The dual epigenetic role of PRMT5 in acute myeloid leukemia: gene activation and repression via histone arginine methylation.

Authors:  S S Tarighat; R Santhanam; D Frankhouser; H S Radomska; H Lai; M Anghelina; H Wang; X Huang; L Alinari; A Walker; M A Caligiuri; C M Croce; L Li; R Garzon; C Li; R A Baiocchi; G Marcucci
Journal:  Leukemia       Date:  2015-11-05       Impact factor: 11.528

6.  Cell cycle control in acute myeloid leukemia.

Authors:  Dominik Schnerch; Jasmin Yalcintepe; Andrea Schmidts; Heiko Becker; Marie Follo; Monika Engelhardt; Ralph Wäsch
Journal:  Am J Cancer Res       Date:  2012-08-20       Impact factor: 6.166

Review 7.  Molecular-based classification of acute myeloid leukemia and its role in directing rational therapy: personalized medicine for profoundly promiscuous proliferations.

Authors:  Gerald B W Wertheim; Elizabeth Hexner; Adam Bagg
Journal:  Mol Diagn Ther       Date:  2012-12       Impact factor: 4.074

8.  Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score.

Authors:  Guido Marcucci; Pearlly Yan; Kati Maharry; David Frankhouser; Deedra Nicolet; Klaus H Metzeler; Jessica Kohlschmidt; Krzysztof Mrózek; Yue-Zhong Wu; Donna Bucci; John P Curfman; Susan P Whitman; Ann-Kathrin Eisfeld; Jason H Mendler; Sebastian Schwind; Heiko Becker; Constance Bär; Andrew J Carroll; Maria R Baer; Meir Wetzler; Thomas H Carter; Bayard L Powell; Jonathan E Kolitz; John C Byrd; Christoph Plass; Ramiro Garzon; Michael A Caligiuri; Richard M Stone; Stefano Volinia; Ralf Bundschuh; Clara D Bloomfield
Journal:  J Clin Oncol       Date:  2013-12-30       Impact factor: 44.544

Review 9.  Myeloproliferation and hematopoietic stem cell dysfunction due to defective Notch receptor modification by O-fucose glycans.

Authors:  Lan Zhou
Journal:  Semin Immunopathol       Date:  2012-03-14       Impact factor: 9.623

10.  Flexible model-based clustering of mixed binary and continuous data: application to genetic regulation and cancer.

Authors:  Fatin N Zainul Abidin; David R Westhead
Journal:  Nucleic Acids Res       Date:  2017-04-20       Impact factor: 16.971
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