Literature DB >> 22095838

Laparoscopic myomectomy focusing on the myoma pseudocapsule: technical and outcome reports.

Andrea Tinelli1, Brad S Hurst, Gernot Hudelist, Daniel Alberto Tsin, Michael Stark, Liselotte Mettler, Marcello Guido, Antonio Malvasi.   

Abstract

BACKGROUND: Our aim was to assess surgical complaints and reproductive outcomes of laparoscopic intracapsular myomectomies by a prospective observational study run in University affiliated hospitals.
METHODS: Between 2005 and 2010, 235 women underwent subserous and intramural laparoscopic myomectomy of fibroids (4-10 cm in diameter) for indications of pelvic pain, menstrual disorders, a large growing myoma or infertility. The main outcome measures were post-surgical parameters, including complications, the need for subsequent surgery or symptomatic relief, resumption of normal life and reproductive outcome.
RESULTS: Pelvic pain occurred in 27%, menorrhagia or metorrhagia in 21%, a large growing myoma in 10% and infertility in 42% of women. Single fibroids occurred in 51.9% of patients while 48.1% had multiple myomas. Of all patients, 58.2% had subserosal and 41.8% had intramural myomas. No laparoscopies were converted to laparotomy. In 3 years, 1.2% of patients had a second laparoscopic myomectomy for recurrent fibroids. The mean total operative laparoscopic time was 84 min (range 25-126 min), with mean blood loss of 118 ± 27.9 ml. By 48 h after surgery, 86.3% were discharged with no major post-operative complications. No late complications, such as bleeding, urinary tract infections or bowel lesions, occurred. Of the women who underwent myomectomy for infertility, 74% finally conceived. At term, 32.9% of patients underwent Caesarean section, 24.8% delivered by vacuum extractor and 42.2% had spontaneous deliveries. No case of uterine rupture occurred.
CONCLUSIONS: Intracapsular subserous and intramural myomectomy saving the fibroid pseudocapsule showed few early and no late surgical complications, enhanced healing by preserving myometrial integrity and allowed a good fertility rate and delivery outcome. In young patients suffering fibroids, laparoscopic intracapsular myomectomy is a potential recommended surgical treatment.

Entities:  

Mesh:

Year:  2011        PMID: 22095838     DOI: 10.1093/humrep/der369

Source DB:  PubMed          Journal:  Hum Reprod        ISSN: 0268-1161            Impact factor:   6.918


  21 in total

1.  Matrix production and remodeling as therapeutic targets for uterine leiomyoma.

Authors:  Caitlin Fujisawa; John J Castellot
Journal:  J Cell Commun Signal       Date:  2014-07-11       Impact factor: 5.782

2.  Moving Toward Individualized Medicine for Uterine Leiomyomas.

Authors:  Shannon K Laughlin-Tommaso; Elizabeth A Stewart
Journal:  Obstet Gynecol       Date:  2018-10       Impact factor: 7.661

3.  The indication and curative effect of hysteroscopic and laparoscopic myomectomy for type II submucous myomas.

Authors:  Haibo Wang; Jinrong Zhao; Xiujuan Li; Ping Li; Caihong Lu; Shujuan Tian; Zhong-hua Wang
Journal:  BMC Surg       Date:  2016-02-27       Impact factor: 2.102

Review 4.  Epidemiology of Uterine Myomas: A Review.

Authors:  Radmila Sparic; Ljiljana Mirkovic; Antonio Malvasi; Andrea Tinelli
Journal:  Int J Fertil Steril       Date:  2015-12-23

5.  Improved Fertility Following Enucleation of Intramural Myomas in Infertile Women.

Authors:  Yu-Cui Tian; Jian-Hong Wu; Hong-Mei Wang; Yin-Mei Dai
Journal:  Chin Med J (Engl)       Date:  2017-07-20       Impact factor: 2.628

6.  Predictors of postoperative hemoglobin drop after laparoscopic myomectomy.

Authors:  Rafał Watrowski; Christoph Jäger; Johannes Forster
Journal:  Wideochir Inne Tech Maloinwazyjne       Date:  2017-03-13       Impact factor: 1.195

7.  Surgical management of neurovascular bundle in uterine fibroid pseudocapsule.

Authors:  Andrea Tinelli; Antonio Malvasi; Brad S Hurst; Daniel A Tsin; Fausto Davila; Guillermo Dominguez; Domenico Dell'edera; Carlo Cavallotti; Roberto Negro; Sarah Gustapane; Chris M Teigland; Liselotte Mettler
Journal:  JSLS       Date:  2012 Jan-Mar       Impact factor: 2.172

Review 8.  The prevalence of occult leiomyosarcoma at surgery for presumed uterine fibroids: a meta-analysis.

Authors:  Elizabeth A Pritts; David J Vanness; Jonathan S Berek; William Parker; Ronald Feinberg; Jacqueline Feinberg; David L Olive
Journal:  Gynecol Surg       Date:  2015-05-19

Review 9.  Uterine fibroids: current perspectives.

Authors:  Aamir T Khan; Manjeet Shehmar; Janesh K Gupta
Journal:  Int J Womens Health       Date:  2014-01-29

10.  Immunohistochemical localization of nerve fibers in the pseudocapsule of fibroids.

Authors:  Y Sun; L Zhu; X Huang; C Zhou; X Zhang
Journal:  Eur J Histochem       Date:  2014-05-08       Impact factor: 3.188

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.