OBJECTIVE: There is a demonstrated association between poor mood and deficiency in several micronutrients. Multivitamin supplements contain a wide range of nutrients, suggesting that they may be effective in improving mood; however, few studies have investigated this potential in randomized, controlled trials. This study investigates the effects of a multivitamin, mineral, and herbal supplement on mood and stress in a group of healthy, older male volunteers. METHODS: In this randomized, double-blind, placebo-controlled trial, fifty men, aged 50-69 years, supplemented for a period of 8 weeks with a multivitamin formulation that contained vitamins (at levels above recommended daily intakes), minerals, antioxidants, and herbal extracts, or a placebo. They completed a series of mood and stress questionnaires at baseline and post-supplementation. RESULTS: Compared with placebo, there was a significant reduction in the overall score on a depression anxiety and stress scale and an improvement in alertness and general daily functioning in the multivitamin group. CONCLUSIONS: Supplementation with a multivitamin, mineral and herbal formulation may be useful in improving alertness and reducing negative mood symptoms and may also improve feelings of general day-to-day well-being.
RCT Entities:
OBJECTIVE: There is a demonstrated association between poor mood and deficiency in several micronutrients. Multivitamin supplements contain a wide range of nutrients, suggesting that they may be effective in improving mood; however, few studies have investigated this potential in randomized, controlled trials. This study investigates the effects of a multivitamin, mineral, and herbal supplement on mood and stress in a group of healthy, older male volunteers. METHODS: In this randomized, double-blind, placebo-controlled trial, fifty men, aged 50-69 years, supplemented for a period of 8 weeks with a multivitamin formulation that contained vitamins (at levels above recommended daily intakes), minerals, antioxidants, and herbal extracts, or a placebo. They completed a series of mood and stress questionnaires at baseline and post-supplementation. RESULTS: Compared with placebo, there was a significant reduction in the overall score on a depression anxiety and stress scale and an improvement in alertness and general daily functioning in the multivitamin group. CONCLUSIONS: Supplementation with a multivitamin, mineral and herbal formulation may be useful in improving alertness and reducing negative mood symptoms and may also improve feelings of general day-to-day well-being.
Authors: Barbara Troesch; Hans K Biesalski; Rolf Bos; Erik Buskens; Philip C Calder; Wim H M Saris; Jörg Spieldenner; Henkjan J Verkade; Peter Weber; Manfred Eggersdorfer Journal: Nutrients Date: 2015-07-21 Impact factor: 5.717
Authors: Jerome Sarris; Katherine H M Cox; David A Camfield; Andrew Scholey; Con Stough; Erin Fogg; Marni Kras; David J White; Avni Sali; Andrew Pipingas Journal: Nutr J Date: 2012-12-14 Impact factor: 3.271
Authors: Rachel C Veasey; Crystal F Haskell-Ramsay; David O Kennedy; Karl Wishart; Silvia Maggini; Caspar J Fuchs; Emma J Stevenson Journal: Nutrients Date: 2015-07-27 Impact factor: 5.717
Authors: Andrew Scholey; Isabelle Bauer; Chris Neale; Karen Savage; David Camfield; David White; Silvia Maggini; Andrew Pipingas; Con Stough; Matthew Hughes Journal: Nutrients Date: 2013-09-13 Impact factor: 5.717
Authors: David A Camfield; Mark A Wetherell; Andrew B Scholey; Katherine H M Cox; Erin Fogg; David J White; Jerome Sarris; Marni Kras; Con Stough; Avni Sali; Andrew Pipingas Journal: Nutrients Date: 2013-11-11 Impact factor: 5.717