BACKGROUND/AIMS: To explore the presenting and early symptoms of dementia with Lewy bodies (DLB). METHOD: Patients with mild dementia fulfilling diagnostic criteria for DLB (n = 61) and Alzheimer's disease (AD) (n = 109) were recruited from outpatient dementia clinics in western Norway. At diagnosis, caregivers were asked which symptom had been the presenting symptom of dementia. RESULTS: Caregivers reported that memory impairment was the most common presenting symptom in DLB (57%), followed by visual hallucinations (44%), depression (34%), problem solving difficulties (33%), gait problems (28%), and tremor/stiffness (25%). In contrast, 99% of AD carers reported impaired memory as a presenting symptom, whereas visual hallucinations were a presenting symptom in 3% of the AD cases. CONCLUSION: DLB should be suspected in predementia cases with visual hallucinations.
BACKGROUND/AIMS: To explore the presenting and early symptoms of dementia with Lewy bodies (DLB). METHOD:Patients with mild dementia fulfilling diagnostic criteria for DLB (n = 61) and Alzheimer's disease (AD) (n = 109) were recruited from outpatientdementia clinics in western Norway. At diagnosis, caregivers were asked which symptom had been the presenting symptom of dementia. RESULTS: Caregivers reported that memory impairment was the most common presenting symptom in DLB (57%), followed by visual hallucinations (44%), depression (34%), problem solving difficulties (33%), gait problems (28%), and tremor/stiffness (25%). In contrast, 99% of AD carers reported impaired memory as a presenting symptom, whereas visual hallucinations were a presenting symptom in 3% of the AD cases. CONCLUSION: DLB should be suspected in predementia cases with visual hallucinations.
Authors: Maria I Lapid; Karen M Kuntz; Sara S Mason; Jeremiah A Aakre; Emily S Lundt; Walter Kremers; Laura A Allen; Daniel A Drubach; Bradley F Boeve Journal: Dement Geriatr Cogn Disord Date: 2017-04-28 Impact factor: 2.959
Authors: Jan-Peter van Wieringen; Jan Booij; Vladimir Shalgunov; Philip Elsinga; Martin C Michel Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 2012-12-09 Impact factor: 3.000
Authors: John D Peipert; Lee A Jennings; Tahmineh Romero; Ron D Hays; Neil S Wenger; Emmett Keeler; David B Reuben Journal: J Am Geriatr Soc Date: 2020-11-30 Impact factor: 5.562