Literature DB >> 22093969

Betaine excretion correlates with plasma homocysteine when plasma lipids are elevated.

Michael Lever1, Sandy Slow, Peter M George, Stephen T Chambers.   

Abstract

OBJECTIVES: To reconcile observing a positive correlation of betaine excretion with homocysteine in lipid disorder patients but not other study groups. DESIGN AND METHODS: Correlations were estimated in subgroups of a control group and the lipid disorder patients.
RESULTS: Plasma non high-density lipoprotein (non-HDL) cholesterol differed (p<0.0001) between the groups. The correlation increased with the median plasma non-HDL cholesterol in subgroups.
CONCLUSIONS: This correlation is associated with patients with elevated plasma lipids.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 22093969     DOI: 10.1016/j.clinbiochem.2011.10.021

Source DB:  PubMed          Journal:  Clin Biochem        ISSN: 0009-9120            Impact factor:   3.281


  3 in total

1.  The contrasting relationships between betaine and homocysteine in two clinical cohorts are associated with plasma lipids and drug treatments.

Authors:  Michael Lever; Peter M George; Wendy Atkinson; Jane L Elmslie; Sandy Slow; Sarah L Molyneux; Richard W Troughton; A Mark Richards; Christopher M Frampton; Stephen T Chambers
Journal:  PLoS One       Date:  2012-03-02       Impact factor: 3.240

2.  Betaine and secondary events in an acute coronary syndrome cohort.

Authors:  Michael Lever; Peter M George; Jane L Elmslie; Wendy Atkinson; Sandy Slow; Sarah L Molyneux; Richard W Troughton; A Mark Richards; Christopher M Frampton; Stephen T Chambers
Journal:  PLoS One       Date:  2012-05-23       Impact factor: 3.240

3.  Variability of plasma and urine betaine in diabetes mellitus and its relationship to methionine load test responses: an observational study.

Authors:  Michael Lever; Sandy Slow; David O McGregor; Warwick J Dellow; Peter M George; Stephen T Chambers
Journal:  Cardiovasc Diabetol       Date:  2012-07-11       Impact factor: 9.951

  3 in total

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