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Literature DB >> 2209373

The mouse model of oxygen-induced retinopathy: a suitable animal model for angiogenesis research.

Abstract

Newborn mice exposed to high (greater than 98%) ambient oxygen during the newborn period and subsequently removed to room air will develop a proliferative retinopathy which mimics the neovascular component of acute retinopathy of prematurity. In this paper, we report preliminary ultrastructural findings on the vitreous new vessels in the mouse model of oxygen-induced retinopathy, and argue that the model is appropriate for research on non surgical treatments for ROP in particular and angiogenesis in general.

Entities: Chemical Disease Species

Mesh：

Substances：
Oxygen

Year: 1990 PMID： 2209373 DOI： 10.1007/bf02482605

Source DB: PubMed Journal: Doc Ophthalmol ISSN： 0012-4486 Impact factor: 2.379

17 in total

1. Experimental approach to the pathogenesis of retrolental fibroplasia. IV. The effects of gradual and of rapid transfer from concentrated oxygen to normal air on the oxygen-induced changes in the eyes of young mice.

Authors: L J GYLLENSTEN; B E HELLSTROM
Journal: Am J Ophthalmol Date: 1956-04 Impact factor: 5.258

2. Experimental studies.

Authors: A PATZ
Journal: Am J Ophthalmol Date: 1955-08 Impact factor: 5.258

3. Effect of high oxygen concentrations on eyes of newborn mice.

Authors: R GERSCHMAN; P W NADIG; A C SNELL; S W NYE
Journal: Am J Physiol Date: 1954-10

4. Experimental approach to the pathogenesis of retrolental fibroplasia. I. Changes of the eye induced by exposure of newborn mice to concentrated oxygen.

Authors: L J GYLLENSTEN; B E HELLSTROM
Journal: Acta Paediatr Suppl Date: 1954

5. Oxygen studies in retrolental fibroplasia. II. The production of the microscopic changes of retrolental fibroplasia in experimental animals.

Authors: A PATZ; A EASTHAM; D H HIGGINBOTHAM; T KLEH
Journal: Am J Ophthalmol Date: 1953-11 Impact factor: 5.258

6. Tumor growth and neovascularization: an experimental model using the rabbit cornea.

Authors: M A Gimbrone; R S Cotran; S B Leapman; J Folkman
Journal: J Natl Cancer Inst Date: 1974-02 Impact factor: 13.506

7. Oxygen studies in retrolental fibroplasia. V. The effect of rapid vs. gradual withdrawal from oxygen on the mouse eye.

Authors: A PATZ; A B EASTHAM
Journal: AMA Arch Ophthalmol Date: 1957-05

The mouse model of oxygen-induced retinopathy: a suitable animal model for angiogenesis research.

1. Experimental approach to the pathogenesis of retrolental fibroplasia. IV. The effects of gradual and of rapid transfer from concentrated oxygen to normal air on the oxygen-induced changes in the eyes of young mice.

2. Experimental studies.

3. Effect of high oxygen concentrations on eyes of newborn mice.

4. Experimental approach to the pathogenesis of retrolental fibroplasia. I. Changes of the eye induced by exposure of newborn mice to concentrated oxygen.

5. Oxygen studies in retrolental fibroplasia. II. The production of the microscopic changes of retrolental fibroplasia in experimental animals.

6. Tumor growth and neovascularization: an experimental model using the rabbit cornea.

7. Oxygen studies in retrolental fibroplasia. V. The effect of rapid vs. gradual withdrawal from oxygen on the mouse eye.

8. Scanning electron microscopic studies of the hyaloid vascular system in newborn mice exposed to O2 and CO2.

9. Oxygen-induced retinopathy in newborn rats: effects of prolonged normobaric and hyperbaric oxygen supplementation.

10. Diabetic neovascularization: permeability and ultrastructure.

1. An elevated level of copper zinc superoxide dismutase fails to prevent oxygen induced retinopathy in mice.

2. Experimental oxygen-induced retinal detachment in the newborn Wistar rat.

Review 3. The effect of oxygen and light on the structure and function of the neonatal rat retina.

Review 4. Update on animal models of diabetic retinopathy: from molecular approaches to mice and higher mammals.

5. Identification of retinopathy of prematurity related miRNAs in hyperoxia-induced neonatal rats by deep sequencing.

Review 6. Angio-LncRs: LncRNAs that regulate angiogenesis and vascular disease.

7. Revisiting the mouse model of oxygen-induced retinopathy.

8. Detection and Quantification of Retinal Neovascularization Using BrdU Incorporation.