Literature DB >> 22093183

Production of 61Cu using natural cobalt target and its separation using ascorbic acid and common anion exchange resin.

Sujata Saha Das1, Sankha Chattopadhyay, Luna Barua, Malay Kanti Das.   

Abstract

(61)Cu was produced by (nat)Co(α, xn)(61)Cu reaction. (61)Cu production yield was 89.5 MBq/μAh (2.42 mCi/μAh) at the end of irradiation (EOI). A simple radiochemical separation method using anion exchange resin and ascorbic acid has been employed to separate the product radionuclide from inactive target material and co-produced non-isotopic impurities. The radiochemical separation yield was about 90%. Radiochemical purity of (61)Cu was >99% 1 h after EOI. Final product was suitable for making complex with N(2)S(2) type of ligands.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 22093183     DOI: 10.1016/j.apradiso.2011.10.011

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  3 in total

1.  Production of GMP-Compliant Clinical Amounts of Copper-61 Radiopharmaceuticals from Liquid Targets.

Authors:  Alexandra I Fonseca; Vítor H Alves; Sérgio J C do Carmo; Magda Silva; Ivanna Hrynchak; Francisco Alves; Amílcar Falcão; Antero J Abrunhosa
Journal:  Pharmaceuticals (Basel)       Date:  2022-06-07

Review 2.  Development of copper based drugs, radiopharmaceuticals and medical materials.

Authors:  Paweł Szymański; Tomasz Frączek; Magdalena Markowicz; Elżbieta Mikiciuk-Olasik
Journal:  Biometals       Date:  2012-08-23       Impact factor: 2.949

Review 3.  The copper radioisotopes: a systematic review with special interest to 64Cu.

Authors:  Artor Niccoli Asabella; Giuseppe Lucio Cascini; Corinna Altini; Domenico Paparella; Antonio Notaristefano; Giuseppe Rubini
Journal:  Biomed Res Int       Date:  2014-05-07       Impact factor: 3.411

  3 in total

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