BACKGROUND: Although hyaluronic acid (HA) fillers are extensively used for the correction of facial wrinkles and folds, there is a limit to patient satisfaction, especially in patients with severe wrinkles. OBJECTIVE: To evaluate the potential for synergistic effects with combined treatment using a nonablative infrared (IR) device and HA filler in the treatment of nasolabial fold (NLF) wrinkles. MATERIALS AND METHODS: This was a split-face randomized study in which 12 Korean patients were treated with HA filler on both NLFs and with a nonablative IR device on the experimental side of the face. Clinical evaluations from subjects and investigators and photographs were obtained at baseline, just before and after the procedures, and 1 and 2 months after completion of the procedures. RESULTS: There were no significant differences between wrinkle severity and global aesthetic scores for HA gel implantation alone and HA gel with nonablative IR device treatment at any point. CONCLUSION: Combining the use of a nonablative IR device with HA filler does not appear to be superior to HA filler alone in the treatment of moderate to severe NLF wrinkles.
RCT Entities:
BACKGROUND: Although hyaluronic acid (HA) fillers are extensively used for the correction of facial wrinkles and folds, there is a limit to patient satisfaction, especially in patients with severe wrinkles. OBJECTIVE: To evaluate the potential for synergistic effects with combined treatment using a nonablative infrared (IR) device and HA filler in the treatment of nasolabial fold (NLF) wrinkles. MATERIALS AND METHODS: This was a split-face randomized study in which 12 Korean patients were treated with HA filler on both NLFs and with a nonablative IR device on the experimental side of the face. Clinical evaluations from subjects and investigators and photographs were obtained at baseline, just before and after the procedures, and 1 and 2 months after completion of the procedures. RESULTS: There were no significant differences between wrinkle severity and global aesthetic scores for HA gel implantation alone and HA gel with nonablative IR device treatment at any point. CONCLUSION: Combining the use of a nonablative IR device with HA filler does not appear to be superior to HA filler alone in the treatment of moderate to severe NLF wrinkles.
Authors: Hyuk Kim; Kui Young Park; Sun Young Choi; Hyun-Ju Koh; Sun-Young Park; Won-Seok Park; Il-Hong Bae; Beom Joon Kim Journal: Ann Dermatol Date: 2014-07-31 Impact factor: 1.444
Authors: Tomasz Stefura; Artur Kacprzyk; Jakub Droś; Marta Krzysztofik; Oksana Skomarovska; Marta Fijałkowska; Mateusz Koziej Journal: Aesthetic Plast Surg Date: 2021-07-13 Impact factor: 2.708