Literature DB >> 22092784

Acellular dermal matrix allograft versus subepithelial connective tissue graft in treatment of gingival recessions: a 5-year randomized clinical study.

Neda Moslemi1, Mahvash Mousavi Jazi, Farideh Haghighati, Seyyedeh Pouya Morovati, Raika Jamali.   

Abstract

AIM: The present randomized clinical trial compared the long-term results of subepithelial connective tissue graft (SCTG) versus acellular dermal matrix allograft (ADMA) in treatment of gingival recessions.
MATERIALS AND METHODS: In 16 patients with bilateral Miller Class I/II gingival recessions, one side was treated with SCTG and the other side with ADMA. Clinical parameters were measured at baseline, 6 months, and at 5 years post-surgery.
RESULTS: Fifteen patients completed the study. At 6 months, all parameters showed significant improvement in ADMA and SCTG groups [complete root coverage (CRC): 73.3% versus 26.7%, p = 0.027; reduction of recession depth (RD): 2.6 ± 1.1 mm versus 2.2 ± 1.1 mm, p = 0.376; reduction of recession width (RW): 3.0 ± 1.4 mm versus 2.4 ± 1.4 mm, p = 0.207 respectively]. At 5 years, significant relapses were detected in CRC and reduction of RD and RW in both groups with no statistically significant difference (CRC: 20.0% versus 13.3%, p = 1.00; RD: 1.6 ± 1.2 mm versus 1.5 ± 1.4mm, p = 0.838; RW: 1.8 ± 1.4 mm versus 1.3 ± 1.5mm, p = 0.367). Patients practicing horizontal toothbrushing habit showed more relapse (OR = 11.2; p = 0.01). Compared with baseline, the gingival width (GW) did not increase in ADMA-treated sites (p = 0.903).
CONCLUSION: Five-year results of SCTG and ADMA were similar in terms of CRC and reduction of RD and RW. Both techniques showed a significant relapse associated with returning to horizontal toothbrushing habit. Increase of GW was stable in SCTG-treated sites, but reached to pre-surgical values in ADMA-treated cases.
© 2011 John Wiley & Sons A/S.

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Year:  2011        PMID: 22092784     DOI: 10.1111/j.1600-051X.2011.01789.x

Source DB:  PubMed          Journal:  J Clin Periodontol        ISSN: 0303-6979            Impact factor:   8.728


  14 in total

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3.  A randomized split mouth clinical study to compare the clinical outcomes of subepithelial connective graft and acellular dermal matrix in Miller's Class I recession coverage therapy.

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4.  Healing of localized gingival recessions treated with a coronally advanced flap alone or combined with an enamel matrix derivative and a porcine acellular dermal matrix: a preclinical study.

Authors:  Y Shirakata; A Sculean; Y Shinohara; K Sena; N Takeuchi; D D Bosshardt; K Noguchi
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5.  Coronally advanced flap achieved higher esthetic outcomes without a connective tissue graft for the treatment of single gingival recessions: a 4-year randomized clinical trial.

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7.  Application of an Acellular Dermal Matrix Allograft (CenoDerm) for Treatment of Multiple Gingival Recession Defects: A Case Report with One-year Follow-up.

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9.  Root coverage using a coronally advanced flap with or without acellular dermal matrix: a meta-analysis.

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10.  Acellular dermal matrix and subepithelial connective tissue grafts for root coverage: A systematic review.

Authors:  Sarah Ivy Gallagher; Debora Candace Matthews
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