Literature DB >> 22091792

Behind-the-counter statins: a silver bullet for reducing costs and increasing access?

Neeraj Sood1, Eric Sun, Xiaohui Zhuo.   

Abstract

OBJECTIVE: To examine how the 2004 introduction of behind-the-counter (BTC) simvastatin in the United Kingdom affected utilization, prices, and expenditures. DATA SOURCES/STUDY
SETTING: Secondary data on simvastatin utilization, prices, and expenditures between 1997 and 2007 in the United Kingdom and four other countries. STUDY
DESIGN: We used a difference-in-differences approach to estimate how the introduction of BTC simvastatin affected utilization, prices, and expenditures. This approach compares outcomes in the United Kingdom before and after the introduction of BTC simvastatin, using outcomes in countries where the drug remained prescription only to control for possible confounders. DATA COLLECTION/EXTRACTION
METHODS: Data on simvastain utilization, prices, and expenditures between 1997 and 2007 in the United Kingdom and four other countries were obtained from an outside vendor. PRINCIPAL
FINDINGS: The introduction of BTC simvastatin in the United Kingdom led to a significant increase in utilization of simvastatin and a significant decline in expenditures for simvastatin purchases. Our results are robust to alternate model specifications.
CONCLUSIONS: Behind-the-counter statins have the potential to simultaneously increase use of statins and lower expenditures. © Health Research and Educational Trust.

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Year:  2011        PMID: 22091792      PMCID: PMC3447239          DOI: 10.1111/j.1475-6773.2011.01315.x

Source DB:  PubMed          Journal:  Health Serv Res        ISSN: 0017-9124            Impact factor:   3.402


  12 in total

1.  Expanding statin use to help more at-risk patients is causing financial heartburn.

Authors:  Mike Mitka
Journal:  JAMA       Date:  2003-11-05       Impact factor: 56.272

2.  OTC statins: a bad decision for public health.

Authors: 
Journal:  Lancet       Date:  2004-05-22       Impact factor: 79.321

3.  Coronary artery disease and hypertension: outcomes of a pharmacist-managed blood pressure program.

Authors:  Karen J McConnell; Emily B Zadvorny; Angela M Hardy; Thomas Delate; Jon R Rasmussen; John A Merenich
Journal:  Pharmacotherapy       Date:  2006-09       Impact factor: 4.705

4.  The effect of the Rx-to-OTC switch of loratadine and changes in prescription drug benefits on utilization and cost of therapy.

Authors:  Patrick W Sullivan; Kavita V Nair; Bimal V Patel
Journal:  Am J Manag Care       Date:  2005-06       Impact factor: 2.229

5.  The Asheville Project: long-term clinical and economic outcomes of a community pharmacy diabetes care program.

Authors:  Carole W Cranor; Barry A Bunting; Dale B Christensen
Journal:  J Am Pharm Assoc (Wash)       Date:  2003 Mar-Apr

6.  The impact of over-the-counter simvastatin on the number of statin prescriptions in the United Kingdom: a view from the General Practice Research Database.

Authors:  Kristian B Filion; J A Chris Delaney; James M Brophy; Pierre Ernst; Samy Suissa
Journal:  Pharmacoepidemiol Drug Saf       Date:  2007-01       Impact factor: 2.890

7.  A randomized trial of the effect of community pharmacist intervention on cholesterol risk management: the Study of Cardiovascular Risk Intervention by Pharmacists (SCRIP).

Authors:  Ross T Tsuyuki; Jeffrey A Johnson; Koon K Teo; Scot H Simpson; Margaret L Ackman; Rosemarie S Biggs; Andrew Cave; Wei-Ching Chang; Vladimir Dzavik; Karen B Farris; Donna Galvin; William Semchuk; Jeff G Taylor
Journal:  Arch Intern Med       Date:  2002-05-27

8.  Reclassification of simvastatin to over-the-counter status in the United Kingdom: a primary prevention strategy.

Authors:  David B Nash; Stephen A Nash
Journal:  Am J Cardiol       Date:  2004-11-04       Impact factor: 2.778

Review 9.  Prescription drug cost sharing: associations with medication and medical utilization and spending and health.

Authors:  Dana P Goldman; Geoffrey F Joyce; Yuhui Zheng
Journal:  JAMA       Date:  2007-07-04       Impact factor: 56.272

Review 10.  Clinical efficacy and safety of statins in managing cardiovascular risk.

Authors:  Navin K Kapur; Kiran Musunuru
Journal:  Vasc Health Risk Manag       Date:  2008
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  1 in total

Review 1.  Over-the-counter medicines: Global perspective and Indian scenario.

Authors:  P A Marathe; S K Kamat; R K Tripathi; S B Raut; N P Khatri
Journal:  J Postgrad Med       Date:  2020 Jan-Mar       Impact factor: 1.476

  1 in total

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