| Literature DB >> 2209094 |
Y Fukushima1, M G Byers, P C Watkins, J C Winkelmann, B G Forget, T B Shows.
Abstract
Type I hereditary spherocytosis results from a molecular defect in the beta-polypeptide of the erythrocyte cytoskeletal protein spectrin. Using a cDNA probe, we had previously assigned the gene for human erythrocyte beta-spectrin (SPTB) to chromosome 14 based upon analysis of its segregation in panels of human x rodent somatic cell hybrids (Winkelmann et al., 1988). Here we report the regional localization of this gene by in situ hybridization to 14q23----q24.2.Entities:
Mesh：
Substances：
Year: 1990 PMID： 2209094 DOI： 10.1159/000132939
Source DB: PubMed Journal: Cytogenet Cell Genet ISSN： 0301-0171