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Literature DB >> 22090471

International Union of Basic and Clinical Pharmacology. LXXXV: calcium-activated chloride channels.

Abstract

Calcium-activated chloride channels (CaCCs) are widely expressed in various tissues and implicated in physiological processes such as sensory transduction, epithelial secretion, and smooth muscle contraction. Transmembrane proteins with unknown function 16 (TMEM16A) has recently been identified as a major component of CaCCs. Detailed molecular analysis of TMEM16A will be needed to understand its structure-function relationships. The role this channel plays in physiological systems remains to be established and is currently a subject of intense investigation.

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Year: 2011 PMID： 22090471 PMCID： PMC3250081 DOI： 10.1124/pr.111.005009

Source DB: PubMed Journal: Pharmacol Rev ISSN： 0031-6997 Impact factor: 25.468

146 in total

1. Differential regulation of Ca(2+)-activated Cl(-) currents in rabbit arterial and portal vein smooth muscle cells by Ca(2+)-calmodulin-dependent kinase.

Authors: I A Greenwood; J Ledoux; N Leblanc
Journal: J Physiol Date: 2001-07-15 Impact factor: 5.182

2. Local uncaging of caged Ca(2+) reveals distribution of Ca(2+)-activated Cl(-) channels in pancreatic acinar cells.

Authors: M K Park; R B Lomax; A V Tepikin; O H Petersen
Journal: Proc Natl Acad Sci U S A Date: 2001-09-04 Impact factor: 11.205

3. Spontaneous Ca2+ activated Cl- currents in isolated urethral smooth muscle cells.

Authors: G P Sergeant; M A Hollywood; N G McHale; K D Thornbury
Journal: J Urol Date: 2001-09 Impact factor: 7.450

4. Anion permeation in Ca(2+)-activated Cl(-) channels.

Authors: Z Qu; H C Hartzell
Journal: J Gen Physiol Date: 2000-12 Impact factor: 4.086

Review 5. TMEM16 proteins: the long awaited calcium-activated chloride channels?

Authors: C A Flores; L P Cid; F V Sepúlveda; M I Niemeyer
Journal: Braz J Med Biol Res Date: 2009-09-25 Impact factor: 2.590

6. Role of gob-5 in mucus overproduction and airway hyperresponsiveness in asthma.

Authors: A Nakanishi; S Morita; H Iwashita; Y Sagiya; Y Ashida; H Shirafuji; Y Fujisawa; O Nishimura; M Fujino
Journal: Proc Natl Acad Sci U S A Date: 2001-04-10 Impact factor: 11.205

7. Anion channels in chara corallina tonoplast membrane: calcium dependence and rectification.

Authors: G Berecki; Z Varga; F Van Iren; B Van Duijn
Journal: J Membr Biol Date: 1999-11-15 Impact factor: 1.843

Review 8. Chloride secretion by the intestinal epithelium: molecular basis and regulatory aspects.

Authors: K E Barrett; S J Keely
Journal: Annu Rev Physiol Date: 2000 Impact factor: 19.318

Review 9. Molecular characteristics and functional diversity of CLCA family members.

Authors: B U Pauli; M Abdel-Ghany; H C Cheng; A D Gruber; H A Archibald; R C Elble
Journal: Clin Exp Pharmacol Physiol Date: 2000-11 Impact factor: 2.557

10. Bimodal control of a Ca(2+)-activated Cl(-) channel by different Ca(2+) signals.

Authors: A Kuruma; H C Hartzell
Journal: J Gen Physiol Date: 2000-01 Impact factor: 4.086

86 in total

1. Structural foundations of optogenetics: Determinants of channelrhodopsin ion selectivity.

Authors: Andre Berndt; Soo Yeun Lee; Jonas Wietek; Charu Ramakrishnan; Elizabeth E Steinberg; Asim J Rashid; Hoseok Kim; Sungmo Park; Adam Santoro; Paul W Frankland; Shrivats M Iyer; Sally Pak; Sofie Ährlund-Richter; Scott L Delp; Robert C Malenka; Sheena A Josselyn; Marie Carlén; Peter Hegemann; Karl Deisseroth
Journal: Proc Natl Acad Sci U S A Date: 2015-12-22 Impact factor: 11.205

2. Two Ca(2+)-Binding Sites Cooperatively Couple Together in TMEM16A Channel.

Authors: Yuebin Han; Suhua Zhang; Shuxi Ren; Yafei Chen; Hongbo Yuan; Ran Chai; Hui Yu; Hailin Zhang; Yong Zhan; Hailong An
Journal: J Membr Biol Date: 2015-12-26 Impact factor: 1.843

3. Divalent cations modulate TMEM16A calcium-activated chloride channels by a common mechanism.

Authors: Hongbo Yuan; Chongsen Gao; Yafei Chen; Mengwen Jia; Jinpeng Geng; Hailin Zhang; Yong Zhan; Linda M Boland; Hailong An
Journal: J Membr Biol Date: 2013-08-31 Impact factor: 1.843

4. Functional reconstitution of a chloride channel bares its soul.

Authors: H Criss Hartzell; Chelsey Chandler Ruppersburg
Journal: Proc Natl Acad Sci U S A Date: 2013-11-14 Impact factor: 11.205

5. Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling.

Authors: Adrian Britschgi; Anke Bill; Heike Brinkhaus; Christopher Rothwell; Ieuan Clay; Stephan Duss; Michael Rebhan; Pichai Raman; Chantale T Guy; Kristie Wetzel; Elizabeth George; M Oana Popa; Sarah Lilley; Hedaythul Choudhury; Martin Gosling; Louis Wang; Stephanie Fitzgerald; Jason Borawski; Jonathan Baffoe; Mark Labow; L Alex Gaither; Mohamed Bentires-Alj
Journal: Proc Natl Acad Sci U S A Date: 2013-02-19 Impact factor: 11.205

10. Preassociated apocalmodulin mediates Ca2+-dependent sensitization of activation and inactivation of TMEM16A/16B Ca2+-gated Cl- channels.

Authors: Tingting Yang; Wayne A Hendrickson; Henry M Colecraft
Journal: Proc Natl Acad Sci U S A Date: 2014-12-08 Impact factor: 11.205