Literature DB >> 22090135

The cellular antiviral restriction factor tetherin does not inhibit poxviral replication.

Katja Sliva1, Theresa Resch, Benjamin Kraus, Christine Goffinet, Oliver T Keppler, Barbara S Schnierle.   

Abstract

Interferon-stimulated genes fulfill innate antiviral effector functions. Among them, tetherin (THN) blocks the release of many enveloped viruses from infected cells. Vaccinia virus (VACV) encodes immune modulators interfering with antiviral host responses. Therefore, it was tempting to study a potential VACV-THN interaction. Remarkably, THN expression did not inhibit VACV release and replication. VACV infection did not diminish THN surface levels or impair its function on retroviral release. This suggests that THN is unable to restrict VACV replication.

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Year:  2011        PMID： 22090135      PMCID： PMC3264375          DOI： 10.1128/JVI.05198-11

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  43 in total

1.  High-speed mass transit for poxviruses on microtubules.

Authors:  B Moss; B M Ward
Journal:  Nat Cell Biol       Date:  2001-11       Impact factor: 28.824

Review 2.  The formation and function of extracellular enveloped vaccinia virus.

Authors:  Geoffrey L Smith; Alain Vanderplasschen; Mansun Law
Journal:  J Gen Virol       Date:  2002-12       Impact factor: 3.891

Review 3.  Poxviruses and immune evasion.

Authors:  Bruce T Seet; J B Johnston; Craig R Brunetti; John W Barrett; Helen Everett; Cheryl Cameron; Joanna Sypula; Steven H Nazarian; Alexandra Lucas; Grant McFadden
Journal:  Annu Rev Immunol       Date:  2001-12-19       Impact factor: 28.527

4.  Mapping of deletions in the genome of the highly attenuated vaccinia virus MVA and their influence on virulence.

Authors:  H Meyer; G Sutter; A Mayr
Journal:  J Gen Virol       Date:  1991-05       Impact factor: 3.891

5.  Significance of extracellular enveloped virus in the in vitro and in vivo dissemination of vaccinia.

Authors:  L G Payne
Journal:  J Gen Virol       Date:  1980-09       Impact factor: 3.891

6.  Replication of modified vaccinia virus Ankara in primary chicken embryo fibroblasts requires expression of the interferon resistance gene E3L.

Authors:  Simone Hornemann; Olof Harlin; Caroline Staib; Sigrid Kisling; Volker Erfle; Bernd Kaspers; Georg Häcker; Gerd Sutter
Journal:  J Virol       Date:  2003-08       Impact factor: 5.103

7.  Plasma membrane budding as an alternative release mechanism of the extracellular enveloped form of vaccinia virus from HeLa cells.

Authors:  Andrea Meiser; Carmen Sancho; Jacomine Krijnse Locker
Journal:  J Virol       Date:  2003-09       Impact factor: 5.103

8.  Mechanism of vaccinia virus release and its specific inhibition by N1-isonicotinoyl-N2-3-methyl-4-chlorobenzoylhydrazine.

Authors:  L G Payne; K Kristenson
Journal:  J Virol       Date:  1979-11       Impact factor: 5.103

Review 9.  Vaccinia virus motility.

Authors:  Geoffrey L Smith; Brendan J Murphy; Mansun Law
Journal:  Annu Rev Microbiol       Date:  2003       Impact factor: 15.500

10.  Characterization of the human endogenous retrovirus K Gag protein: identification of protease cleavage sites.

Authors:  Benjamin Kraus; Klaus Boller; Andreas Reuter; Barbara S Schnierle
Journal:  Retrovirology       Date:  2011-03-23       Impact factor: 4.602
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