Literature DB >> 22087058

Experience from the use of absorbable type I collagen as haemostatic agent in obstetric and gynecological operations.

V Karagiannis, A Daniilidis, D Rousso, V Palapelas, T Karagiannis, D Kiskinis.   

Abstract

UNLABELLED: During the third stage of labour there are a lot of causes of significant hemorrhage. The commonest causes of acute hemorrhage are the uterine atony, the retained placenta, the lower tract lacerations, uterine rupture, placenta accreta, hereditary coagulopathy. Also, there could be significant bleeding, during caesarian section, usually at the time of removal of the placenta in cases of low lying placenta or placenta previa. A lot of times we have to confront serious hemorrhages in gynecological procedures like hysterectomies in cases of cervical, uterine or ovarian cancers. In order to deal with these problems successfully, general and specific measures are being taken. In cases of atonic uterus when all the other methods are unsuccessful we have to proceed to ligation of the internal iliac artery or even hysterectomy. MATERIAL-
METHODS: We have tried to use the hemostatic type I collagen in obstetrical and gynecological cases in order to control the bleeding. We have used the collagen type I totally in 8 cases. Five of them were cases of atonic uterus after normal delivery or caesarian section and three of them were gynecological cases of uterine fibroids and ovarian cancer.
RESULTS: By placing the collagen type I over the bleeding surfaces we have realized that in a very short period of time, there has been satisfactory control of the bleeding and immediate clinical improvement of the patient. In four out of five obstetrical cases that we have used the type I collagen, we have managed to avoid the hysterectomy.

Entities:  

Keywords:  Type I collagen; caesarian section; gynecological operations; post partum hemorrhage

Year:  2006        PMID: 22087058      PMCID: PMC2464255     

Source DB:  PubMed          Journal:  Hippokratia        ISSN: 1108-4189            Impact factor:   0.471


  7 in total

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Journal:  Am J Obstet Gynecol       Date:  1993-08       Impact factor: 8.661

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Review 4.  Uterine artery embolization: an underused method of controlling pelvic hemorrhage.

Authors:  S Vedantham; S C Goodwin; B McLucas; G Mohr
Journal:  Am J Obstet Gynecol       Date:  1997-04       Impact factor: 8.661

5.  Massive pelvic hemorrhage during gynecologic cancer surgery: "pack and go back".

Authors:  M A Finan; J V Fiorica; M S Hoffman; D P Barton; N Gleeson; W S Roberts; D Cavanagh
Journal:  Gynecol Oncol       Date:  1996-09       Impact factor: 5.482

6.  Calin from Hirudo medicinalis, an inhibitor of von Willebrand factor binding to collagen under static and flow conditions.

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Journal:  Blood       Date:  1995-02-01       Impact factor: 22.113

7.  Use of absorbable collagen for hemostasis in general surgical patients.

Authors:  I W Browder; M S Litwin
Journal:  Am Surg       Date:  1986-09       Impact factor: 0.688

  7 in total
  1 in total

Review 1.  Use of Monsel solution to treat obstetrical hemorrhage: a review and comparison to other topical hemostatic agents.

Authors:  Devin T Miller; Dana M Roque; Alessandro D Santin
Journal:  Am J Obstet Gynecol       Date:  2015-01-08       Impact factor: 8.661

  1 in total

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