BACKGROUND: A prospective cohort study design gives the opportunity for identification, update of different exposures and their verification by biomarker measurements. The aim of The Polish Mother and Child Cohort Study (REPRO_PL) is to evaluate the impact of exposure to different environmental factors during pregnancy and, after birth, on the pregnancy outcome, children's health and neurodevelopment. MATERIALS AND METHODS: REPRO_PL cohort was established in 2007. From the cohort of 1300 mother-child pairs, 300 children are followed-up until they are two years old to asses the exposure, health status and neurodevelopment. Children are examined twice: at one and two years of age by a pediatrician and a psychologist/child development specialist. During each visit, detailed questionnaire is conducted with the mothers and supplemented with the information from the medical charts to have appropriate recognition of the child's health and development. Additionally, the current health status of the child is checked and his/her biometry is performed. A urine sample is collected from each child for the verification of environmental tobacco smoke (ETS) and polycyclic aromatic hydrocarbons (PAH) exposure. Some children have a blood sample collected for the assessment of the lead and cadmium levels. Child's neurodevelopment is assessed based on Bayley Scales for Infant and Toddler Development (Bayley-III). RESULTS AND CONCLUSIONS: The results of the study will become available within the next few years and will help to determine the impact of the environmental exposures on children's health and neurodevelopment. REPRO_PL cohort is a middle-sized cohort, very much focused on specific research questions with the potential for future extension and cooperation.
BACKGROUND: A prospective cohort study design gives the opportunity for identification, update of different exposures and their verification by biomarker measurements. The aim of The Polish Mother and Child Cohort Study (REPRO_PL) is to evaluate the impact of exposure to different environmental factors during pregnancy and, after birth, on the pregnancy outcome, children's health and neurodevelopment. MATERIALS AND METHODS: REPRO_PL cohort was established in 2007. From the cohort of 1300 mother-child pairs, 300 children are followed-up until they are two years old to asses the exposure, health status and neurodevelopment. Children are examined twice: at one and two years of age by a pediatrician and a psychologist/child development specialist. During each visit, detailed questionnaire is conducted with the mothers and supplemented with the information from the medical charts to have appropriate recognition of the child's health and development. Additionally, the current health status of the child is checked and his/her biometry is performed. A urine sample is collected from each child for the verification of environmental tobacco smoke (ETS) and polycyclic aromatic hydrocarbons (PAH) exposure. Some children have a blood sample collected for the assessment of the lead and cadmium levels. Child's neurodevelopment is assessed based on Bayley Scales for Infant and Toddler Development (Bayley-III). RESULTS AND CONCLUSIONS: The results of the study will become available within the next few years and will help to determine the impact of the environmental exposures on children's health and neurodevelopment. REPRO_PL cohort is a middle-sized cohort, very much focused on specific research questions with the potential for future extension and cooperation.
Authors: Kinga Polanska; Anna Krol; Dorota Merecz-Kot; Danuta Ligocka; Karolina Mikolajewska; Fiorino Mirabella; Flavia Chiarotti; Gemma Calamandrei; Wojciech Hanke Journal: Int J Environ Res Public Health Date: 2017-07-17 Impact factor: 3.390
Authors: Flavia Ruggieri; Costanza Majorani; Francesco Domanico; Alessandro Alimonti Journal: Int J Environ Res Public Health Date: 2017-05-12 Impact factor: 3.390
Authors: Ewelina Wesołowska; Agnieszka Jankowska; Elżbieta Trafalska; Paweł Kałużny; Mariusz Grzesiak; Jolanta Dominowska; Wojciech Hanke; Gemma Calamandrei; Kinga Polańska Journal: Int J Environ Res Public Health Date: 2019-03-02 Impact factor: 3.390
Authors: Kinga Polanska; Wojciech Hanke; Wojciech Sobala; Malgorzata Trzcinka-Ochocka; Danuta Ligocka; Slawomir Brzeznicki; Halina Strugala-Stawik; Per Magnus Journal: Biomed Res Int Date: 2013-09-26 Impact factor: 3.411
Authors: Jolanta Gromadzinska; Kinga Polanska; Lucyna Kozlowska; Karolina Mikolajewska; Iwona Stelmach; Joanna Jerzyńska; Włodzimierz Stelmach; Mariusz Grzesiak; Wojciech Hanke; Wojciech Wasowicz Journal: Int J Environ Res Public Health Date: 2018-06-12 Impact factor: 3.390