Literature DB >> 22085754

Antioxidant activities of polysaccharides from Lentinus edodes and their significance for disease prevention.

Huoliang Chen1, Ying Ju, Junjie Li, Min Yu.   

Abstract

The crude polysaccharide (LEP) was extracted by hot water from the fruiting bodies of Lentinus edodes, and further purified by DEAE-cellulose and Sepharose CL-6B chromatography, giving three polysaccharide fractions coded as LEPA1, LEPB1 and LEPC1. In this study, their chemical and physical characteristics of polysaccharide fractions and antioxidant capacities, including scavenging activity against hydroxyl radicals, superoxide radicals and Fe(2+)-chelating ability, were valuated. The results showed that LEPC1 exhibited significantly antioxidant activity at a concentration-dependent manner. Therefore these results indicated that the water-extractable polysaccharide fraction was a potent antioxidant and could be developed to be new health medicine for fighting against various human diseases.
Copyright © 2011 Elsevier B.V. All rights reserved.

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Year:  2011        PMID: 22085754     DOI: 10.1016/j.ijbiomac.2011.10.027

Source DB:  PubMed          Journal:  Int J Biol Macromol        ISSN: 0141-8130            Impact factor:   6.953


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