Literature DB >> 22085739

Mathematical modeling of transport and degradation of feedstuffs in the small intestine.

Masoomeh Taghipoor1, Philippe Lescoat, Jean-René Licois, Christine Georgelin, Guy Barles.   

Abstract

We describe a mathematical model of digestion in the small intestine. The main interest of our work is to consider simultaneously the different aspects of digestion i.e. transport of the bolus all along the intestine, feedstuffs degradation according to the enzymes and local physical conditions, and nutrients absorption. A system of coupled ordinary differential equations is used to model these phenomena. The major unknowns of this system are the position of the bolus and its composition. This system of equations is solved numerically. We present several numerical computations for the degradation, absorption and transport of the bolus with acceptable accuracy regarding the overall behavior of the model and also when challenged versus experimental data. The main feature and interest of this model are its genericity. Even if we are at an early stage of development, our approach can be adapted to deal with contrasted feedstuffs in non-ruminant animal to predict the composition and velocity of bolus in the small intestine.
Copyright © 2011 Elsevier Ltd. All rights reserved.

Mesh:

Year:  2011        PMID: 22085739     DOI: 10.1016/j.jtbi.2011.10.024

Source DB:  PubMed          Journal:  J Theor Biol        ISSN: 0022-5193            Impact factor:   2.691


  4 in total

1.  A Multiphase Flow in the Antroduodenal Portion of the Gastrointestinal Tract: A Mathematical Model.

Authors:  P V Trusov; N V Zaitseva; M R Kamaltdinov
Journal:  Comput Math Methods Med       Date:  2016-06-19       Impact factor: 2.238

2.  A Spatially Continuous Model of Carbohydrate Digestion and Transport Processes in the Colon.

Authors:  Arun S Moorthy; Stephen P J Brooks; Martin Kalmokoff; Hermann J Eberl
Journal:  PLoS One       Date:  2015-12-17       Impact factor: 3.240

3.  In silico modelling of mass transfer & absorption in the human gut.

Authors:  T E Moxon; O Gouseti; S Bakalis
Journal:  J Food Eng       Date:  2016-05       Impact factor: 5.354

4.  Effect of chyme viscosity and nutrient feedback mechanism on gastric emptying.

Authors:  Thomas E Moxon; Philippe Nimmegeers; Dries Telen; Peter J Fryer; Jan Van Impe; Serafim Bakalis
Journal:  Chem Eng Sci       Date:  2017-11-02       Impact factor: 4.311

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.