Literature DB >> 22085248

Palladium-catalyzed synthesis of 4-aminophthalazin-1(2H)-ones by isocyanide insertion.

Tjøstil Vlaar1, Eelco Ruijter, Anass Znabet, Elwin Janssen, Frans J J de Kanter, Bert U W Maes, Romano V A Orru.   

Abstract

Palladium-catalyzed cross-coupling of a wide range of substituted o-(pseudo)halobenzoates and hydrazines with isocyanide insertion followed by lactamization efficiently affords 4-aminophthalazin-1(2H)-ones that are difficult to obtain regioselectively by classical methods.

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Year:  2011        PMID: 22085248     DOI: 10.1021/ol202784d

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Catalytic Isonitrile Insertions and Condensations Initiated by RNC-X Complexation.

Authors:  Suravi Chakrabarty; Shruti Choudhary; Arpit Doshi; Fa-Qiang Liu; Rishabh Mohan; Manasa P Ravindra; Dhruv Shah; Xun Yang; Fraser F Fleming
Journal:  Adv Synth Catal       Date:  2014-06-20       Impact factor: 5.837

2.  Amino- and polyaminophthalazin-1(2H)-ones: synthesis, coordination properties, and biological activity.

Authors:  Zbigniew Malinowski; Emilia Fornal; Agata Sumara; Renata Kontek; Karol Bukowski; Beata Pasternak; Dariusz Sroczyński; Joachim Kusz; Magdalena Małecka; Monika Nowak
Journal:  Beilstein J Org Chem       Date:  2021-02-25       Impact factor: 2.883

  2 in total

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