Literature DB >> 22084388

The Renaissance or the cuckoo clock.

Jonathon Pines1, Iain Hagan.   

Abstract

'…in Italy, for thirty years under the Borgias, they had warfare, terror, murder and bloodshed, but they produced Michelangelo, Leonardo da Vinci and the Renaissance. In Switzerland, they had brotherly love, they had five hundred years of democracy and peace-and what did that produce? The cuckoo clock'. Orson Welles as Harry Lime: The Third Man. Orson Welles might have been a little unfair on the Swiss, after all cuckoo clocks were developed in the Schwartzwald, but, more importantly, Swiss democracy gives remarkably stable government with considerable decision-making at the local level. The alternative is the battling city-states of Renaissance Italy: culturally rich but chaotic at a higher level of organization. As our understanding of the cell cycle improves, it appears that the cell is organized more along the lines of Switzerland than Renaissance Italy, and one major challenge is to determine how local decisions are made and coordinated to produce the robust cell cycle mechanisms that we observe in the cell as a whole.

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Year:  2011        PMID: 22084388      PMCID: PMC3203460          DOI: 10.1098/rstb.2011.0080

Source DB:  PubMed          Journal:  Philos Trans R Soc Lond B Biol Sci        ISSN: 0962-8436            Impact factor:   6.237


  112 in total

1.  Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation.

Authors:  R E Carazo-Salas; G Guarguaglini; O J Gruss; A Segref; E Karsenti; I W Mattaj
Journal:  Nature       Date:  1999-07-08       Impact factor: 49.962

2.  Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint.

Authors:  Lucia Sironi; Marina Mapelli; Stefan Knapp; Anna De Antoni; Kuan-Teh Jeang; Andrea Musacchio
Journal:  EMBO J       Date:  2002-05-15       Impact factor: 11.598

3.  Polar gradients of the DYRK-family kinase Pom1 couple cell length with the cell cycle.

Authors:  Sophie G Martin; Martine Berthelot-Grosjean
Journal:  Nature       Date:  2009-05-27       Impact factor: 49.962

Review 4.  From promiscuity to precision: protein phosphatases get a makeover.

Authors:  David M Virshup; Shirish Shenolikar
Journal:  Mol Cell       Date:  2009-03-13       Impact factor: 17.970

5.  Structure of kinetochore fibers: microtubule continuity and inter-microtubule bridges.

Authors:  P L Witt; H Ris; G G Borisy
Journal:  Chromosoma       Date:  1981       Impact factor: 4.316

6.  Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex.

Authors:  Laura Hewitt; Anthony Tighe; Stefano Santaguida; Anne M White; Clifford D Jones; Andrea Musacchio; Stephen Green; Stephen S Taylor
Journal:  J Cell Biol       Date:  2010-07-12       Impact factor: 10.539

7.  Release of Mps1 from kinetochores is crucial for timely anaphase onset.

Authors:  Nannette Jelluma; Tobias B Dansen; Tale Sliedrecht; Nicholas P Kwiatkowski; Geert J P L Kops
Journal:  J Cell Biol       Date:  2010-10-11       Impact factor: 10.539

8.  Singularity in polarization: rewiring yeast cells to make two buds.

Authors:  Audrey S Howell; Natasha S Savage; Sam A Johnson; Indrani Bose; Allison W Wagner; Trevin R Zyla; H Frederik Nijhout; Michael C Reed; Andrew B Goryachev; Daniel J Lew
Journal:  Cell       Date:  2009-11-13       Impact factor: 41.582

9.  Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction.

Authors:  Stefano Santaguida; Claudio Vernieri; Fabrizio Villa; Andrea Ciliberto; Andrea Musacchio
Journal:  EMBO J       Date:  2011-03-15       Impact factor: 11.598

10.  Kinetochore stretching inactivates the spindle assembly checkpoint.

Authors:  Kazuhiko S K Uchida; Kentaro Takagaki; Kazuki Kumada; Youko Hirayama; Tetsuo Noda; Toru Hirota
Journal:  J Cell Biol       Date:  2009-02-02       Impact factor: 10.539

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  12 in total

Review 1.  Polo-like kinases: structural variations lead to multiple functions.

Authors:  Sihem Zitouni; Catarina Nabais; Swadhin Chandra Jana; Adán Guerrero; Mónica Bettencourt-Dias
Journal:  Nat Rev Mol Cell Biol       Date:  2014-07       Impact factor: 94.444

Review 2.  The biochemistry of mitosis.

Authors:  Samuel Wieser; Jonathon Pines
Journal:  Cold Spring Harb Perspect Biol       Date:  2015-02-06       Impact factor: 10.005

3.  Cell cycle-dependent binding between Cyclin B1 and Cdk1 revealed by time-resolved fluorescence correlation spectroscopy.

Authors:  Martina Barbiero; Luca Cirillo; Sapthaswaran Veerapathiran; Catherine Coates; Camilla Ruffilli; Jonathon Pines
Journal:  Open Biol       Date:  2022-06-29       Impact factor: 7.124

Review 4.  Temporal control of epigenetic centromere specification.

Authors:  Luis P Valente; Mariana C C Silva; Lars E T Jansen
Journal:  Chromosome Res       Date:  2012-07       Impact factor: 5.239

5.  The cell cycle.

Authors:  Tim Hunt; Kim Nasmyth; Béla Novák
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2011-12-27       Impact factor: 6.237

6.  CDK-1 Inhibition in G2 Stabilizes Kinetochore-Microtubules in the following Mitosis.

Authors:  A Sophia Gayek; Ryoma Ohi
Journal:  PLoS One       Date:  2016-06-09       Impact factor: 3.240

7.  Rereplication in emi1-deficient zebrafish embryos occurs through a Cdh1-mediated pathway.

Authors:  Mara E Robu; Yong Zhang; Jennifer Rhodes
Journal:  PLoS One       Date:  2012-10-17       Impact factor: 3.240

8.  A PP1-PP2A phosphatase relay controls mitotic progression.

Authors:  Agnes Grallert; Elvan Boke; Anja Hagting; Ben Hodgson; Yvonne Connolly; John R Griffiths; Duncan L Smith; Jonathon Pines; Iain M Hagan
Journal:  Nature       Date:  2014-12-10       Impact factor: 49.962

9.  The kinetics of G2 and M transitions regulated by B cyclins.

Authors:  Yehong Huang; R Michael Sramkoski; James W Jacobberger
Journal:  PLoS One       Date:  2013-12-04       Impact factor: 3.240

10.  Cyclin B1-Cdk1 facilitates MAD1 release from the nuclear pore to ensure a robust spindle checkpoint.

Authors:  Mark Jackman; Chiara Marcozzi; Martina Barbiero; Mercedes Pardo; Lu Yu; Adam L Tyson; Jyoti S Choudhary; Jonathon Pines
Journal:  J Cell Biol       Date:  2020-06-01       Impact factor: 10.539

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