Literature DB >> 22083914

New flavanones from the leaves of Cryptocarya chinensis and their antituberculosis activity.

Tsung-Hsien Chou1, Jih-Jung Chen, Chien-Fang Peng, Ming-Jen Cheng, Ih-Sheng Chen.   

Abstract

Four new flavanones, cryptoflavanones A-D (1-4, resp.), together with eight known compounds, were isolated from the leaves of Cryptocarya chinensis. The structures of these new compounds were determined by spectral analyses. Among the isolated compounds, pinocembrin (5) and cryptocaryone (6) exhibited antituberculosis activity against Mycobacterium tuberculosis H(37) Rv strain in vitro with MIC values of 3.5 and 25.0 μg/ml, respectively.
Copyright © 2011 Verlag Helvetica Chimica Acta AG, Zürich.

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Year:  2011        PMID： 22083914     DOI： 10.1002/cbdv.201000367

Source DB:  PubMed          Journal:  Chem Biodivers        ISSN： 1612-1872            Impact factor:   2.408


  9 in total

1.  Constituents of an extract of Cryptocarya rubra housed in a repository with cytotoxic and glucose transport inhibitory effects.

Authors:  Yulin Ren; Chunhua Yuan; Yanrong Qian; Hee-Byung Chai; Xiaozhuo Chen; Michael Goetz; A Douglas Kinghorn
Journal:  J Nat Prod       Date:  2013-12-17       Impact factor: 4.050

2.  Antiproliferative effects of methanolic extracts of Cryptocarya concinna Hance roots on oral cancer Ca9-22 and CAL 27 cell lines involving apoptosis, ROS induction, and mitochondrial depolarization.

Authors:  Hurng-Wern Huang; Yi-An Chung; Hsun-Shuo Chang; Jen-Yang Tang; Ih-Sheng Chen; Hsueh-Wei Chang
Journal:  ScientificWorldJournal       Date:  2014-10-15

3.  Investigation of the anti-TB potential of selected propolis constituents using a molecular docking approach.

Authors:  Mohammad Tuhin Ali; Natalia Blicharska; Jamil A Shilpi; Veronique Seidel
Journal:  Sci Rep       Date:  2018-08-16       Impact factor: 4.379

Review 4.  Pharmacological Small Molecules against Prostate Cancer by Enhancing Function of Death Receptor 5.

Authors:  Xia Gan; Yonghong Liu; Xueni Wang
Journal:  Pharmaceuticals (Basel)       Date:  2022-08-21

Review 5.  Promising Antimycobacterial Activities of Flavonoids against Mycobacterium sp. Drug Targets: A Comprehensive Review.

Authors:  Ali A Rabaan; Saad Alhumaid; Hawra Albayat; Mohammed Alsaeed; Fadwa S Alofi; Mawaheb H Al-Howaidi; Safaa A Turkistani; Salah M Alhajri; Hejji E Alahmed; Abdulwahab B Alzahrani; Mutaib M Mashraqi; Sara Alwarthan; Mashael Alhajri; Fatimah S Alshahrani; Souad A Almuthree; Roua A Alsubki; Abdulmonem A Abuzaid; Mubarak Alfaresi; Mona A Al Fares; Abbas Al Mutair
Journal:  Molecules       Date:  2022-08-22       Impact factor: 4.927

6.  TIPdb: a database of anticancer, antiplatelet, and antituberculosis phytochemicals from indigenous plants in Taiwan.

Authors:  Ying-Chi Lin; Chia-Chi Wang; Ih-Sheng Chen; Jhao-Liang Jheng; Jih-Heng Li; Chun-Wei Tung
Journal:  ScientificWorldJournal       Date:  2013-05-12

Review 7.  Pinocembrin: a novel natural compound with versatile pharmacological and biological activities.

Authors:  Azhar Rasul; Faya Martin Millimouno; Wafa Ali Eltayb; Muhammad Ali; Jiang Li; Xiaomeng Li
Journal:  Biomed Res Int       Date:  2013-08-05       Impact factor: 3.411

8.  Antiproliferation of Cryptocarya concinna-derived cryptocaryone against oral cancer cells involving apoptosis, oxidative stress, and DNA damage.

Authors:  Hsun-Shuo Chang; Jen-Yang Tang; Ching-Yu Yen; Hurng-Wern Huang; Chang-Yi Wu; Yi-An Chung; Hui-Ru Wang; Ih-Sheng Chen; Ming-Yii Huang; Hsueh-Wei Chang
Journal:  BMC Complement Altern Med       Date:  2016-03-08       Impact factor: 3.659

Review 9.  Chemical constituents and bioactivity of Formosan lauraceous plants.

Authors:  Hsun-Shuo Chang; Ih-Sheng Chen
Journal:  J Food Drug Anal       Date:  2016-01-05       Impact factor: 6.157
  9 in total

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