PURPOSE: Gastrointestinal metastasis is not common in recurrent non-small-cell lung cancer (NSCLC) patients. There is thus limited information on clinical outcome for these patients. This report presents the clinical characteristics and outcomes of patients with gastrointestinal metastasis after pulmonary resection. METHODS: The study retrospectively analyzed nine NSCLC patients with gastrointestinal metastases. RESULTS: Gastrointestinal metastases were observed in the small intestine (n = 4), colon or rectum (n = 4), and stomach (n = 1). All of the patients were symptomatic. The median survival after gastrointestinal recurrence was 10.8 months. Gastrointestinal surgery was performed in five patients, whereas no cancer treatment was indicated in the remaining four patients. Three patients who underwent surgery for a solitary metastasis survived for more than 2 years after surgery with no other recurrence. CONCLUSION: Surgical resection of gastrointestinal metastasis is indicated not only for symptom relief but also for providing a potentially long-term survival if the patients are properly selected.
PURPOSE:Gastrointestinal metastasis is not common in recurrent non-small-cell lung cancer (NSCLC) patients. There is thus limited information on clinical outcome for these patients. This report presents the clinical characteristics and outcomes of patients with gastrointestinal metastasis after pulmonary resection. METHODS: The study retrospectively analyzed nine NSCLCpatients with gastrointestinal metastases. RESULTS:Gastrointestinal metastases were observed in the small intestine (n = 4), colon or rectum (n = 4), and stomach (n = 1). All of the patients were symptomatic. The median survival after gastrointestinal recurrence was 10.8 months. Gastrointestinal surgery was performed in five patients, whereas no cancer treatment was indicated in the remaining four patients. Three patients who underwent surgery for a solitary metastasis survived for more than 2 years after surgery with no other recurrence. CONCLUSION: Surgical resection of gastrointestinal metastasis is indicated not only for symptom relief but also for providing a potentially long-term survival if the patients are properly selected.
Authors: Hiroshi Sugimura; Francis C Nichols; Ping Yang; Mark S Allen; Stephen D Cassivi; Claude Deschamps; Brent A Williams; Peter C Pairolero Journal: Ann Thorac Surg Date: 2007-02 Impact factor: 4.330
Authors: I Yoshino; T Yohena; M Kitajima; C Ushijima; K Nishioka; Y Ichinose; K Sugimachi Journal: Ann Thorac Cardiovasc Surg Date: 2001-08 Impact factor: 1.520
Authors: Min Soo Kim; Eun Hee Kook; Se Han Ahn; Se Young Jeon; Jung Ho Yoon; Min Sung Han; Cheol Hyeon Kim; Jae Cheol Lee Journal: J Cancer Res Clin Oncol Date: 2008-05-30 Impact factor: 4.553