[A case report-bleeding from the ulcer of wound for mastectomy after postoperative chemotherapy with bevacizumab for Sigmoid colon cancer].

We report the case of a 65-year-old woman with a delayed radiation ulcer and bleeding caused by bevacizumab. She has been undergoing chemotherapy for advanced colon cancer for two years. She received a mastectomy and adjuvant chemoradiotherapy for right breast cancer twenty-one years ago, and colon cancer with liver metastasis was detected using PET two years ago. Since last year she has been treated with bevacizumab chemotherapy bevacizumab due to increased liver metastases. As a result, her radiation ulcer worsened and bleeding occurred repeatedly. On suspicion of an adverse event, we stopped the bevacizumab, and that improved the radiation ulcer and the bleeding. In this case, we discussed radiation induced ulcers, wound healing, and adverse events caused by bevacizumab.