INTRODUCTION: Due to large and increasing numbers of cancer survivors, long-term cancer-related health issues have become a major focus of attention. This study examined the relation between a high-intensity physical rehabilitation program and return-to-work in cancer survivors who had received chemotherapy. METHODS: The intervention group, consisting of 72 cancer survivors from one hospital (8 men and 64 women, mean age 49 years), followed an 18-weeks rehabilitation program including strength and interval training, and home-based activities. An age-matched control group, consisting of 38 cancer survivors (9 men and 29 women), was recruited from two other hospitals. They received only standard medical care. All subjects were evaluated during a telephone interview on employment issues, conducted at ±3 years after diagnosis. The main outcomes were change in working hours per week and time until return-to-work. RESULTS: Patients in the intervention group showed significant less reduction in working hours per week [-5.0 h/week vs. -10.8 h/week (P = .03)]. Multivariate analyses showed that the training intervention, the age of patients, and the number of working hours pre-diagnosis could explain the improvement in long-term participation at work. Time until (partial) return-to-work was 11.5 weeks for the intervention group versus 13.2 weeks for the control group (P = .40). On long-term follow-up, 78% of the participants from the intervention group versus 66% from the control group had returned to work on the pre-diagnosis level of working hours (P = .18). CONCLUSION:Rehabilitation using high-intensity physical training is useful for working patients to minimize the decreased ability to work resulting from cancer and its treatment.
RCT Entities:
INTRODUCTION: Due to large and increasing numbers of cancer survivors, long-term cancer-related health issues have become a major focus of attention. This study examined the relation between a high-intensity physical rehabilitation program and return-to-work in cancer survivors who had received chemotherapy. METHODS: The intervention group, consisting of 72 cancer survivors from one hospital (8 men and 64 women, mean age 49 years), followed an 18-weeks rehabilitation program including strength and interval training, and home-based activities. An age-matched control group, consisting of 38 cancer survivors (9 men and 29 women), was recruited from two other hospitals. They received only standard medical care. All subjects were evaluated during a telephone interview on employment issues, conducted at ±3 years after diagnosis. The main outcomes were change in working hours per week and time until return-to-work. RESULTS:Patients in the intervention group showed significant less reduction in working hours per week [-5.0 h/week vs. -10.8 h/week (P = .03)]. Multivariate analyses showed that the training intervention, the age of patients, and the number of working hours pre-diagnosis could explain the improvement in long-term participation at work. Time until (partial) return-to-work was 11.5 weeks for the intervention group versus 13.2 weeks for the control group (P = .40). On long-term follow-up, 78% of the participants from the intervention group versus 66% from the control group had returned to work on the pre-diagnosis level of working hours (P = .18). CONCLUSION: Rehabilitation using high-intensity physical training is useful for working patients to minimize the decreased ability to work resulting from cancer and its treatment.
Authors: A G E M de Boer; J H A M Verbeek; E R Spelten; A L J Uitterhoeve; A C Ansink; T M de Reijke; M Kammeijer; M A G Sprangers; F J H van Dijk Journal: Br J Cancer Date: 2008-03-18 Impact factor: 7.640
Authors: Olga Husson; Floortje Mols; Lonneke van de Poll-Franse; Jolanda de Vries; Goof Schep; Melissa S Y Thong Journal: Support Care Cancer Date: 2015-01-06 Impact factor: 3.603
Authors: Kelly Kenzik; Maria Pisu; Shelley A Johns; Tamara Baker; Robert A Oster; Elizabeth Kvale; Mona N Fouad; Michelle Y Martin Journal: Pain Med Date: 2015-03-20 Impact factor: 3.750
Authors: Ellen Burke Beckjord; Kerry A Reynolds; G J van Londen; Rachel Burns; Reema Singh; Sarah R Arvey; Stephanie A Nutt; Ruth Rechis Journal: J Psychosoc Oncol Date: 2014
Authors: A J Tevaarwerk; J W Lee; M E Sesto; K A Buhr; C S Cleeland; J Manola; L I Wagner; V T S Chang; M J Fisch Journal: J Cancer Surviv Date: 2013-02-02 Impact factor: 4.442
Authors: Janet S de Moor; Catherine M Alfano; Erin E Kent; Wynne E Norton; Diarmuid Coughlan; Megan C Roberts; Melvin Grimes; Cathy J Bradley Journal: J Natl Cancer Inst Date: 2018-10-01 Impact factor: 13.506