OBJECTIVE: Knowledge of factors impacting adolescents' ability to adhere to their inflammatory bowel disease (IBD) regimen is limited. The current study examines the collective impact of barriers to adherence and anxiety/depressive symptoms on adolescent adherence to the IBD regimen. METHODS: Adolescents (n = 79) completed measures of barriers to adherence, adherence, and anxiety/depressive symptoms at one of two specialty pediatric IBD clinics. RESULTS: Most adolescents reported barriers to adherence and 1 in 8 reported borderline or clinically elevated levels of anxiety/depressive symptoms. Anxiety/depressive symptoms moderated the relationship between barriers to adherence and adherence. Post hoc probing revealed a significant, additive effect of higher anxiety/depressive symptoms in the barriers-adherence relationship, with adherence significantly lower among adolescents with higher barriers and higher anxiety/depressive symptoms. CONCLUSIONS: In order to optimize adherence in adolescents, interventions should target not only barriers to adherence but also any anxiety/depressive symptoms that may negatively impact efforts to adhere to recommended treatment.
OBJECTIVE: Knowledge of factors impacting adolescents' ability to adhere to their inflammatory bowel disease (IBD) regimen is limited. The current study examines the collective impact of barriers to adherence and anxiety/depressive symptoms on adolescent adherence to the IBD regimen. METHODS: Adolescents (n = 79) completed measures of barriers to adherence, adherence, and anxiety/depressive symptoms at one of two specialty pediatric IBD clinics. RESULTS: Most adolescents reported barriers to adherence and 1 in 8 reported borderline or clinically elevated levels of anxiety/depressive symptoms. Anxiety/depressive symptoms moderated the relationship between barriers to adherence and adherence. Post hoc probing revealed a significant, additive effect of higher anxiety/depressive symptoms in the barriers-adherence relationship, with adherence significantly lower among adolescents with higher barriers and higher anxiety/depressive symptoms. CONCLUSIONS: In order to optimize adherence in adolescents, interventions should target not only barriers to adherence but also any anxiety/depressive symptoms that may negatively impact efforts to adhere to recommended treatment.
Authors: J S Hyams; G D Ferry; F S Mandel; J D Gryboski; P M Kibort; B S Kirschner; A M Griffiths; A J Katz; R J Grand; J T Boyle Journal: J Pediatr Gastroenterol Nutr Date: 1991-05 Impact factor: 2.839
Authors: Rachel Neff Greenley; Jennifer Hauser Kunz; Vincent Biank; Alfonso Martinez; Adrian Miranda; Joshua Noe; Grzegorz Telega; Neelesh Ajit Tipnis; Steven Werlin; Michael C Stephens Journal: Inflamm Bowel Dis Date: 2011-08-29 Impact factor: 5.325
Authors: S T Hauser; A M Jacobson; P Lavori; J I Wolfsdorf; R D Herskowitz; J E Milley; R Bliss; D Wertlieb; J Stein Journal: J Pediatr Psychol Date: 1990-08
Authors: S Lichtiger; D H Present; A Kornbluth; I Gelernt; J Bauer; G Galler; F Michelassi; S Hanauer Journal: N Engl J Med Date: 1994-06-30 Impact factor: 91.245
Authors: Kevin A Hommel; Wendy N Gray; Elizabeth Hente; Katherine Loreaux; Richard F Ittenbach; Michele Maddux; Robert Baldassano; Francisco Sylvester; Wallace Crandall; Charles Doarn; Melvin B Heyman; David Keljo; Lee A Denson Journal: Contemp Clin Trials Date: 2015-05-21 Impact factor: 2.226
Authors: Christopher Andrew Lamb; Nicholas A Kennedy; Tim Raine; Philip Anthony Hendy; Philip J Smith; Jimmy K Limdi; Bu'Hussain Hayee; Miranda C E Lomer; Gareth C Parkes; Christian Selinger; Kevin J Barrett; R Justin Davies; Cathy Bennett; Stuart Gittens; Malcolm G Dunlop; Omar Faiz; Aileen Fraser; Vikki Garrick; Paul D Johnston; Miles Parkes; Jeremy Sanderson; Helen Terry; Daniel R Gaya; Tariq H Iqbal; Stuart A Taylor; Melissa Smith; Matthew Brookes; Richard Hansen; A Barney Hawthorne Journal: Gut Date: 2019-09-27 Impact factor: 23.059
Authors: Marina Arvanitis; Darren A DeWalt; Christopher F Martin; Millie D Long; Wenli Chen; Beth Jaeger; Robert S Sandler; Michael D Kappelman Journal: J Pediatr Date: 2016-05-02 Impact factor: 4.406
Authors: Jamie L Ryan; Michael W Mellon; Katherine W F Junger; Elizabeth A Hente; Lee A Denson; Shehzad A Saeed; Kevin A Hommel Journal: Inflamm Bowel Dis Date: 2013-11 Impact factor: 5.325
Authors: Bharati Kochar; Christopher F Martin; Michael D Kappelman; Brennan M Spiegel; Wenli Chen; Robert S Sandler; Millie D Long Journal: Am J Gastroenterol Date: 2017-08-29 Impact factor: 10.864