Literature DB >> 22080234

Catechin protects against oxidative stress and inflammatory-mediated cardiotoxicity in adriamycin-treated rats.

Tarek A Abd El-Aziz1, Randa H Mohamed, Heba F Pasha, Hisham R Abdel-Aziz.   

Abstract

Catechin has anti-inflammatory and antioxidative effects. Cardiotoxicity, which results from intense cardiac oxidative stress and inflammation, is the main limiting factor of the adriamycin use in the treatment of malignant tumors. Thus, the present study aimed to assess the antioxidant and anti-inflammatory effects of catechin on adriamycin-induced cardiotoxicity in rats. Forty-five rats were allocated to three groups: control group, adriamycin group and adriamycin + catechin group. We performed the following measurements: lipid peroxidation (MDA), catalase (CAT), glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) activities as well as, the expression of inflammatory cytokines genes namely nuclear factor kappa-B, tumor necrosis factor and inducible nitric oxide synthase. Catechin administration significantly decreased MDA level and significantly increased CAT, GSH-Px and SOD activities. Also, catechin significantly decreased the expression levels of inflammatory cytokines. Catechin provided cardioprotection on adriamycin-induced cardiotoxicity through their antioxidant and anti-inflammatory properties.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 22080234     DOI： 10.1007/s10238-011-0165-2

Source DB:  PubMed          Journal:  Clin Exp Med        ISSN： 1591-8890            Impact factor:   3.984


  32 in total

1.  Green tea polyphenols inhibit human vascular smooth muscle cell proliferation stimulated by native low-density lipoprotein.

Authors:  Rudolf Locher; Luca Emmanuele; Paolo M Suter; Wilhelm Vetter; Matthias Barton
Journal:  Eur J Pharmacol       Date:  2002-01-02       Impact factor: 4.432

2.  A modified spectrophotometric assay of superoxide dismutase.

Authors:  P Kakkar; B Das; P N Viswanathan
Journal:  Indian J Biochem Biophys       Date:  1984-04       Impact factor: 1.918

3.  Glutathione peroxidase.

Authors:  A Wendel
Journal:  Methods Enzymol       Date:  1981       Impact factor: 1.600

Review 4.  The inducible nitric oxide synthase in vascular and cardiac tissue.

Authors:  J C Stoclet; B Muller; K György; R Andriantsiothaina; A L Kleschyov
Journal:  Eur J Pharmacol       Date:  1999-06-30       Impact factor: 4.432

5.  Tetrathiomolybdate protects against cardiac damage by doxorubicin in mice.

Authors:  Guoqing Hou; Robert Dick; Gerald D Abrams; George J Brewer
Journal:  J Lab Clin Med       Date:  2005-11

6.  Baroreflex sensitivity and oxidative stress in adriamycin-induced heart failure.

Authors:  E Rabelo; K De Angelis; P Bock; T Gatelli Fernandes; F Cervo; A Belló Klein; N Clausell; M Cláudia Irigoyen
Journal:  Hypertension       Date:  2001-09       Impact factor: 10.190

7.  Augmented expression of neuronal nitric oxide synthase in the atria parasympathetically decreases heart rate during acute myocardial infarction in rats.

Authors:  Yoshihito Takimoto; Takeshi Aoyama; Koichi Tanaka; Reiko Keyamura; Yoshiki Yui; Shigetake Sasayama
Journal:  Circulation       Date:  2002-01-29       Impact factor: 29.690

8.  Adriamycin-induced early changes in myocardial antioxidant enzymes and their modulation by probucol.

Authors:  T Li; P K Singal
Journal:  Circulation       Date:  2000-10-24       Impact factor: 29.690

9.  (-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB.

Authors:  Y L Lin; J K Lin
Journal:  Mol Pharmacol       Date:  1997-09       Impact factor: 4.436

10.  Activation of nuclear factor-kappaB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: the role of hydrogen peroxide.

Authors:  Suwei Wang; Srigiridhar Kotamraju; Eugene Konorev; Shasi Kalivendi; Joy Joseph; Balaraman Kalyanaraman
Journal:  Biochem J       Date:  2002-11-01       Impact factor: 3.857
View more
  28 in total

1.  All-trans-retinoic acid ameliorates doxorubicin-induced cardiotoxicity: in vivo potential involvement of oxidative stress, inflammation, and apoptosis via caspase-3 and p53 down-expression.

Authors:  Asmaa F Khafaga; Yasser S El-Sayed
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2017-10-30       Impact factor: 3.000

Review 2.  The value of the Brazilian açai fruit as a therapeutic nutritional strategy for chronic kidney disease patients.

Authors:  Isabelle C V S Martins; Natália A Borges; Peter Stenvinkel; Bengt Lindholm; Hervé Rogez; Maria C N Pinheiro; José L M Nascimento; Denise Mafra
Journal:  Int Urol Nephrol       Date:  2018-06-18       Impact factor: 2.370

3.  Postnatal exposure to voluntary exercise but not the antioxidant catechin protects the vasculature after a switch to an atherogenic environment in middle-age mice.

Authors:  Francois Leblond; Albert Nguyen; Virginie Bolduc; Jean Lambert; Carol Yu; Natacha Duquette; Eric Thorin
Journal:  Pflugers Arch       Date:  2013-01-06       Impact factor: 3.657

4.  Protection from doxorubicin-induced nephrotoxicity by clindamycin: novel antioxidant, anti-inflammatory and anti-apoptotic roles.

Authors:  Kamilia M Ibrahim; Eman M Mantawy; Mona M Elanany; Hend S Abdelgawad; Nuha M Khalifa; Rada H Hussien; Nermeen N El-Agroudy; Ebtehal El-Demerdash
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2019-12-18       Impact factor: 3.000

5.  Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats.

Authors:  Sri Pragnya Cheruku; Grandhi Venkata Ramalingayya; Mallikarjuna Rao Chamallamudi; Subhankar Biswas; Krishnadas Nandakumar; Madhavan Nampoothiri; Karthik Gourishetti; Nitesh Kumar
Journal:  Cytotechnology       Date:  2017-09-13       Impact factor: 2.058

6.  Cardioprotective effects of sitagliptin against doxorubicin-induced cardiotoxicity in rats.

Authors:  Dina S El-Agamy; Hany M Abo-Haded; Mohamed A Elkablawy
Journal:  Exp Biol Med (Maywood)       Date:  2016-04-01

7.  Nephroprotective effect of catechin on gentamicin-induced experimental nephrotoxicity.

Authors:  Ankush Sardana; Sanjeev Kalra; Deepa Khanna; Pitchai Balakumar
Journal:  Clin Exp Nephrol       Date:  2014-05-14       Impact factor: 2.801

8.  Fisetin, a plant flavonoid ameliorates doxorubicin-induced cardiotoxicity in experimental rats: the decisive role of caspase-3, COX-II, cTn-I, iNOs and TNF-α.

Authors:  Tao Ma; Amit D Kandhare; Anwesha A Mukherjee-Kandhare; Subhash L Bodhankar
Journal:  Mol Biol Rep       Date:  2018-10-25       Impact factor: 2.316

9.  Oral treatment with the herbal formula B307 alleviates cardiac toxicity in doxorubicin-treated mice via suppressing oxidative stress, inflammation, and apoptosis.

Authors:  Chia-Ying Lien; Tai-Yuan Chuang; Chih-Hsiang Hsu; Ching-Lung Lin; Sheue-Er Wang; Shuenn-Jyi Sheu; Chiang-Ting Chien; Chung-Hsin Wu
Journal:  Onco Targets Ther       Date:  2015-05-26       Impact factor: 4.147

Review 10.  Inflammation suppression in doxorubicin-induced cardiotoxicity: natural compounds as therapeutic options.

Authors:  Fatemeh Yarmohammadi; Hedyieh Karbasforooshan; A Wallace Hayes; Gholamreza Karimi
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2021-08-05       Impact factor: 3.000
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.