Literature DB >> 22079331

Targeted immunosuppression: no longer naïve.

Robert S Hagan, Jonathan D Powell.   

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Year:  2011        PMID： 22079331      PMCID： PMC3598017          DOI： 10.1016/j.clim.2011.10.004

Source DB:  PubMed          Journal:  Clin Immunol        ISSN： 1521-6616            Impact factor:   3.969


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  15 in total

1.  A central role for mTOR kinase in homeostatic proliferation induced CD8+ T cell memory and tumor immunity.

Authors:  Qingsheng Li; Rajesh R Rao; Koichi Araki; Kristen Pollizzi; Kunle Odunsi; Jonathan D Powell; Protul A Shrikant
Journal:  Immunity       Date:  2011-04-22       Impact factor: 31.745

Review 2.  Phosphoinositide 3-kinase and its targets in B-cell and T-cell signaling.

Authors:  David A Fruman
Journal:  Curr Opin Immunol       Date:  2004-06       Impact factor: 7.486

3.  The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment.

Authors:  Greg M Delgoffe; Thomas P Kole; Yan Zheng; Paul E Zarek; Krystal L Matthews; Bo Xiao; Paul F Worley; Sara C Kozma; Jonathan D Powell
Journal:  Immunity       Date:  2009-06-19       Impact factor: 31.745

Review 4.  Resistance to MEK inhibitors: should we co-target upstream?

Authors:  Poulikos I Poulikakos; David B Solit
Journal:  Sci Signal       Date:  2011-03-29       Impact factor: 8.192

5.  Phase I pharmacokinetic and pharmacodynamic study of the oral MAPK/ERK kinase inhibitor PD-0325901 in patients with advanced cancers.

Authors:  Patricia M LoRusso; Smitha S Krishnamurthi; John J Rinehart; Lisle M Nabell; Lisa Malburg; Paul B Chapman; Samuel E DePrimo; Steven Bentivegna; Keith D Wilner; Weiwei Tan; Alejandro D Ricart
Journal:  Clin Cancer Res       Date:  2010-03-09       Impact factor: 12.531

6.  The pharmacology of mTOR inhibition.

Authors:  David A Guertin; David M Sabatini
Journal:  Sci Signal       Date:  2009-04-21       Impact factor: 8.192

Review 7.  The RSK factors of activating the Ras/MAPK signaling cascade.

Authors:  Audrey Carriere; Hind Ray; John Blenis; Philippe P Roux
Journal:  Front Biosci       Date:  2008-05-01

Review 8.  Molecular mechanisms of mTOR-mediated translational control.

Authors:  Xiaoju Max Ma; John Blenis
Journal:  Nat Rev Mol Cell Biol       Date:  2009-04-02       Impact factor: 94.444

9.  The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.

Authors:  Greg M Delgoffe; Kristen N Pollizzi; Adam T Waickman; Emily Heikamp; David J Meyers; Maureen R Horton; Bo Xiao; Paul F Worley; Jonathan D Powell
Journal:  Nat Immunol       Date:  2011-02-27       Impact factor: 25.606

10.  mTOR regulates memory CD8 T-cell differentiation.

Authors:  Koichi Araki; Alexandra P Turner; Virginia Oliva Shaffer; Shivaprakash Gangappa; Susanne A Keller; Martin F Bachmann; Christian P Larsen; Rafi Ahmed
Journal:  Nature       Date:  2009-06-21       Impact factor: 49.962
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