Literature DB >> 22079167

The many faces of aspartate kinases.

Renaud Dumas1, David Cobessi, Adeline Y Robin, Jean-Luc Ferrer, Gilles Curien.   

Abstract

Based on recent X-ray structures and biochemical characterizations of aspartate kinases from different species, we show in this review how various organizations of a regulatory domain have contributed to the different mechanisms of control observed in aspartate kinases allowing simple to complex allosteric controls in branched pathways. The aim of this review is to show the relationships between domain organization, effector binding sites, mechanism of inhibition and regulatory function of an allosteric enzyme in a biosynthetic pathway. Copyright Â
© 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID： 22079167     DOI： 10.1016/j.abb.2011.10.016

Source DB:  PubMed          Journal:  Arch Biochem Biophys        ISSN： 0003-9861            Impact factor:   4.013


  10 in total

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Journal:  Cell       Date:  2016-03-10       Impact factor: 41.582

2.  Aspartate deficiency limits peptidoglycan synthesis and sensitizes cells to antibiotics targeting cell wall synthesis in Bacillus subtilis.

Authors:  Heng Zhao; Daniel M Roistacher; John D Helmann
Journal:  Mol Microbiol       Date:  2018-08-20       Impact factor: 3.501

3.  Structural insight into the arginine-binding specificity of CASTOR1 in amino acid-dependent mTORC1 signaling.

Authors:  Jing Xia; Rong Wang; Tianlong Zhang; Jianping Ding
Journal:  Cell Discov       Date:  2016-09-13       Impact factor: 10.849

4.  Structural mechanism for the arginine sensing and regulation of CASTOR1 in the mTORC1 signaling pathway.

Authors:  Zhongchao Gai; Qian Wang; Can Yang; Lei Wang; Wei Deng; Geng Wu
Journal:  Cell Discov       Date:  2016-12-27       Impact factor: 10.849

5.  Mechanism of arginine sensing by CASTOR1 upstream of mTORC1.

Authors:  Robert A Saxton; Lynne Chantranupong; Kevin E Knockenhauer; Thomas U Schwartz; David M Sabatini
Journal:  Nature       Date:  2016-08-03       Impact factor: 49.962

6.  Dynamic energy correlation analysis of E. coli aspartokinase III and alteration of allosteric regulation by manipulating energy transduction pathways.

Authors:  Shizhen Wang; Chengwei Ma; An-Ping Zeng
Journal:  Eng Life Sci       Date:  2021-03-02       Impact factor: 2.678

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Authors:  Weihong Min; Huiying Li; Hongmei Li; Chunlei Liu; Jingsheng Liu
Journal:  Int J Mol Sci       Date:  2015-11-27       Impact factor: 5.923

8.  Co-expression of bacterial aspartate kinase and adenylylsulfate reductase genes substantially increases sulfur amino acid levels in transgenic alfalfa (Medicago sativa L.).

Authors:  Zongyong Tong; Can Xie; Lei Ma; Liping Liu; Yongsheng Jin; Jiangli Dong; Tao Wang
Journal:  PLoS One       Date:  2014-02-10       Impact factor: 3.240

9.  Crystal structure of Clostridium acetobutylicum Aspartate kinase (CaAK): An important allosteric enzyme for amino acids production.

Authors:  Babu A Manjasetty; Mark R Chance; Stephen K Burley; Santosh Panjikar; Steven C Almo
Journal:  Biotechnol Rep (Amst)       Date:  2014-09-01

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Authors:  Shashi Kant Singh; Tzu-Ying Sung; Tsui-Yun Chung; Shao-Yu Lin; Sang-Chu Lin; Jo-Chien Liao; Wei-Yu Hsieh; Ming-Hsiun Hsieh
Journal:  Sci Rep       Date:  2018-08-07       Impact factor: 4.379
  10 in total

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