Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 miRNA profiling for biomarker discovery in multiple sclerosis: from microarray to deep sequencing.

Literature DB >> 22078708

miRNA profiling for biomarker discovery in multiple sclerosis: from microarray to deep sequencing.

Mireia Guerau-de-Arellano¹, Hansjuerg Alder, Hatice Gulcin Ozer, Amy Lovett-Racke, Michael K Racke.

Abstract

MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the post-transcriptional level. miRNAs are highly expressed in cells of the immune and nervous system, attesting to their importance in Neuroimmunology. Besides their involvement in modulation of physiological and pathological processes, miRNAs hold high promise as disease biomarkers, therapeutic agents and/or drug targets. Several studies have recently explored the involvement of miRNAs in Multiple Sclerosis (MS) using a variety of miRNA profiling techniques. In this review, we discuss basic miRNA biology and nomenclature, the techniques available for miRNA profiling research and recent miRNA profiling studies in Multiple Sclerosis.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：
Biomarkers
MicroRNAs

Year: 2011 PMID： 22078708 PMCID： PMC3288464 DOI： 10.1016/j.jneuroim.2011.10.006

Source DB: PubMed Journal: J Neuroimmunol ISSN： 0165-5728 Impact factor: 3.478

63 in total

1. Human RISC couples microRNA biogenesis and posttranscriptional gene silencing.

Authors: Richard I Gregory; Thimmaiah P Chendrimada; Neil Cooch; Ramin Shiekhattar
Journal: Cell Date: 2005-11-03 Impact factor: 41.582

2. Combinatorial microRNA target predictions.

Authors: Azra Krek; Dominic Grün; Matthew N Poy; Rachel Wolf; Lauren Rosenberg; Eric J Epstein; Philip MacMenamin; Isabelle da Piedade; Kristin C Gunsalus; Markus Stoffel; Nikolaus Rajewsky
Journal: Nat Genet Date: 2005-04-03 Impact factor: 38.330

3. miR-181a is an intrinsic modulator of T cell sensitivity and selection.

Authors: Qi-Jing Li; Jacqueline Chau; Peter J R Ebert; Giselle Sylvester; Hyeyoung Min; Gwen Liu; Ravi Braich; Muthiah Manoharan; Juergen Soutschek; Petra Skare; Lawrence O Klein; Mark M Davis; Chang-Zheng Chen
Journal: Cell Date: 2007-03-22 Impact factor: 41.582

4. A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA).

Authors: Mirco Castoldi; Sabine Schmidt; Vladimir Benes; Mikkel Noerholm; Andreas E Kulozik; Matthias W Hentze; Martina U Muckenthaler
Journal: RNA Date: 2006-03-15 Impact factor: 4.942

5. MicroRNA targeting specificity in mammals: determinants beyond seed pairing.

Authors: Andrew Grimson; Kyle Kai-How Farh; Wendy K Johnston; Philip Garrett-Engele; Lee P Lim; David P Bartel
Journal: Mol Cell Date: 2007-07-06 Impact factor: 17.970

6. Accumulation of miR-155 and BIC RNA in human B cell lymphomas.

Authors: Peggy S Eis; Wayne Tam; Liping Sun; Amy Chadburn; Zongdong Li; Mario F Gomez; Elsebet Lund; James E Dahlberg
Journal: Proc Natl Acad Sci U S A Date: 2005-02-28 Impact factor: 11.205

Review 7. miRNAs and their potential for use against cancer and other diseases.

Authors: Esmerina Tili; Jean-Jacques Michaille; Varsha Gandhi; William Plunkett; Deepa Sampath; George Adrian Calin
Journal: Future Oncol Date: 2007-10 Impact factor: 3.404

8. MicroRNA-373 induces expression of genes with complementary promoter sequences.

Authors: Robert F Place; Long-Cheng Li; Deepa Pookot; Emily J Noonan; Rajvir Dahiya
Journal: Proc Natl Acad Sci U S A Date: 2008-01-28 Impact factor: 11.205

9. Real-time quantification of microRNAs by stem-loop RT-PCR.

Authors: Caifu Chen; Dana A Ridzon; Adam J Broomer; Zhaohui Zhou; Danny H Lee; Julie T Nguyen; Maura Barbisin; Nan Lan Xu; Vikram R Mahuvakar; Mark R Andersen; Kai Qin Lao; Kenneth J Livak; Karl J Guegler
Journal: Nucleic Acids Res Date: 2005-11-27 Impact factor: 16.971

10. Aberrant T cell differentiation in the absence of Dicer.

Authors: Stefan A Muljo; K Mark Ansel; Chryssa Kanellopoulou; David M Livingston; Anjana Rao; Klaus Rajewsky
Journal: J Exp Med Date: 2005-07-11 Impact factor: 14.307

25 in total

1. Integration of MicroRNA databases to study MicroRNAs associated with multiple sclerosis.

Authors: Charlotte Angerstein; Michael Hecker; Brigitte Katrin Paap; Dirk Koczan; Madhan Thamilarasan; Hans-Jürgen Thiesen; Uwe Klaus Zettl
Journal: Mol Neurobiol Date: 2012-05-02 Impact factor: 5.590

2. MiR-125a-5p Regulates Vitamin D Receptor Expression in a Mouse Model of Experimental Autoimmune Encephalomyelitis.

Authors: Han-Chun Long; Rui Wu; Chun-Feng Liu; Fei-Long Xiong; Zu Xu; Dian He; Yi-Fan Zhang; Bing Shao; Ping-An Zhang; Guang-Yin Xu; Lan Chu
Journal: Neurosci Bull Date: 2019-08-19 Impact factor: 5.203

3. Dysregulated RNA-Induced Silencing Complex (RISC) Assembly within CNS Corresponds with Abnormal miRNA Expression during Autoimmune Demyelination.

Authors: Przemysław Lewkowicz; Hanna Cwiklińska; Marcin P Mycko; Maria Cichalewska; Małgorzata Domowicz; Natalia Lewkowicz; Anna Jurewicz; Krzysztof W Selmaj
Journal: J Neurosci Date: 2015-05-13 Impact factor: 6.167

Review 4. Systematic approaches to central nervous system myelin.

Authors: Patricia de Monasterio-Schrader; Olaf Jahn; Stefan Tenzer; Sven P Wichert; Julia Patzig; Hauke B Werner
Journal: Cell Mol Life Sci Date: 2012-03-23 Impact factor: 9.261

5. Mir-223 regulates the number and function of myeloid-derived suppressor cells in multiple sclerosis and experimental autoimmune encephalomyelitis.

Authors: Claudia Cantoni; Francesca Cignarella; Laura Ghezzi; Bob Mikesell; Bryan Bollman; Melissa M Berrien-Elliott; Aaron R Ireland; Todd A Fehniger; Gregory F Wu; Laura Piccio
Journal: Acta Neuropathol Date: 2016-10-04 Impact factor: 17.088

6. A Nanobiosensor Based on Fluorescent DNA-Hosted Silver Nanocluster and HCR Amplification for Detection of MicroRNA Involved in Progression of Multiple Sclerosis.

Authors: Niloofar Mansourian; Mahdi Rahaie; Morteza Hosseini
Journal: J Fluoresc Date: 2017-05-06 Impact factor: 2.217

Review 7. Multiple Sclerosis.

Authors: Daniel S Reich; Claudia F Lucchinetti; Peter A Calabresi
Journal: N Engl J Med Date: 2018-01-11 Impact factor: 91.245