Literature DB >> 22078146

An outbreak of severe respiratory tract infection due to human metapneumovirus in a long-term care facility for the elderly in Oregon.

Robert S Liao1, Dianna M Appelgate, Robert K Pelz.   

Abstract

Human metapneumovirus (hMPV) was demonstrated to be responsible for an outbreak of acute respiratory tract infection with high morbidity and mortality among residents of a long-term care facility for the elderly during the late spring-summer in Oregon. Respiratory virus infections are a common cause of death in the elderly and the burden of human metapneumovirus may be underestimated. This case report stresses the importance of hMPV in causing outbreaks in long-term care facilities for the elderly. Cough and elevated temperature were common to all the resident patient cases. Six resident patient cases had hMPV laboratory confirmation of which 5 had the diagnosis of pneumonia and 4 were hospitalized. The fatality rate was 33.3% among laboratory confirmed cases and 31.3.0% among probable resident patient cases. The signs and symptoms observed in the elderly with acute respiratory infection caused by hMPV are difficult to distinguish from those associated with other respiratory viruses and direct testing for hMPV with molecular methods should be routinely pursued to prevent nosocomial infections.
Copyright © 2011 Elsevier B.V. All rights reserved.

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Year:  2011        PMID: 22078146     DOI: 10.1016/j.jcv.2011.10.010

Source DB:  PubMed          Journal:  J Clin Virol        ISSN: 1386-6532            Impact factor:   3.168


  18 in total

Review 1.  Modulation of Host Immunity by the Human Metapneumovirus.

Authors:  Pablo F Céspedes; Christian E Palavecino; Alexis M Kalergis; Susan M Bueno
Journal:  Clin Microbiol Rev       Date:  2016-10       Impact factor: 26.132

2.  Practical Guidance for Clinical Microbiology Laboratories: Viruses Causing Acute Respiratory Tract Infections.

Authors:  Carmen L Charlton; Esther Babady; Christine C Ginocchio; Todd F Hatchette; Robert C Jerris; Yan Li; Mike Loeffelholz; Yvette S McCarter; Melissa B Miller; Susan Novak-Weekley; Audrey N Schuetz; Yi-Wei Tang; Ray Widen; Steven J Drews
Journal:  Clin Microbiol Rev       Date:  2018-12-12       Impact factor: 26.132

Review 3.  Severe Respiratory Viral Infections: New Evidence and Changing Paradigms.

Authors:  James M Walter; Richard G Wunderink
Journal:  Infect Dis Clin North Am       Date:  2017-07-05       Impact factor: 5.982

4.  Burden of human metapneumovirus infection in young children.

Authors:  Kathryn M Edwards; Yuwei Zhu; Marie R Griffin; Geoffrey A Weinberg; Caroline B Hall; Peter G Szilagyi; Mary A Staat; Marika Iwane; Mila M Prill; John V Williams
Journal:  N Engl J Med       Date:  2013-02-14       Impact factor: 91.245

5.  Beyond flu: Trends in respiratory infection outbreaks in Ontario healthcare settings from 2007 to 2017, and implications for non-influenza outbreak management.

Authors:  Katherine Paphitis; Camille Achonu; Sandra Callery; Jonathan Gubbay; Kevin Katz; Matthew Muller; Herveen Sachdeva; Bryna Warshawsky; Michael Whelan; Gary Garber; Michelle Murti
Journal:  Can Commun Dis Rep       Date:  2021-06-09

Review 6.  Human metapneumovirus in adults.

Authors:  Lenneke E M Haas; Steven F T Thijsen; Leontine van Elden; Karen A Heemstra
Journal:  Viruses       Date:  2013-01-08       Impact factor: 5.048

7.  Outbreaks of human metapneumovirus in two skilled nursing facilities -West Virginia and Idaho, 2011-2012.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2013-11-22       Impact factor: 17.586

8.  Lower Respiratory Tract Infection in a Renal Transplant Recipient: Do not Forget Metapneumovirus.

Authors:  N Noel; B Rammaert; J Zuber; N Sayre; M F Mamzer-Bruneel; M Leruez-Ville; L Mascard; M Lecuit; O Lortholary
Journal:  Case Rep Transplant       Date:  2012-11-14

9.  Performance of a rapid human metapneumovirus antigen test during an outbreak in a long-term care facility.

Authors:  N Hamada; K Hara; Y Matsuo; Y Imamura; T Kashiwagi; Y Nakazono; K Gotoh; Y Ohtsu; E Ohtaki; T Motohiro; H Watanabe
Journal:  Epidemiol Infect       Date:  2013-05-23       Impact factor: 4.434

Review 10.  Respiratory Syncytial Virus and Other Noninfluenza Respiratory Viruses in Older Adults.

Authors:  Fumihiro Kodama; David A Nace; Robin L P Jump
Journal:  Infect Dis Clin North Am       Date:  2017-12       Impact factor: 5.982

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