Literature DB >> 22076504

Opening the field of integrin biology to "biased agonism".

Daniel I Simon.   

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Year:  2011        PMID： 22076504      PMCID： PMC4086858          DOI： 10.1161/CIRCRESAHA.111.257980

Source DB:  PubMed          Journal:  Circ Res        ISSN： 0009-7330            Impact factor:   17.367


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  27 in total

1.  A simple, no-wash cell adhesion-based high-throughput assay for the discovery of small-molecule regulators of the integrin CD11b/CD18.

Authors:  Jun Y Park; M Amin Arnaout; Vineet Gupta
Journal:  J Biomol Screen       Date:  2007-04

Review 2.  Beta-arrestin-biased ligands at seven-transmembrane receptors.

Authors:  Jonathan D Violin; Robert J Lefkowitz
Journal:  Trends Pharmacol Sci       Date:  2007-07-20       Impact factor: 14.819

3.  Mac-1 signaling via Src-family and Syk kinases results in elastase-dependent thrombohemorrhagic vasculopathy.

Authors:  Junichi Hirahashi; Divya Mekala; Jessica Van Ziffle; Ling Xiao; Simin Saffaripour; Denisa D Wagner; Steven D Shapiro; Clifford Lowell; Tanya N Mayadas
Journal:  Immunity       Date:  2006-07-27       Impact factor: 31.745

4.  A MAC-1 attack: integrin functions directly challenged in knockout mice.

Authors:  E F Plow; L Zhang
Journal:  J Clin Invest       Date:  1997-03-15       Impact factor: 14.808

5.  Identification and reconstruction of the binding site within alphaMbeta2 for a specific and high affinity ligand, NIF.

Authors:  L Zhang; E F Plow
Journal:  J Biol Chem       Date:  1997-07-11       Impact factor: 5.157

6.  Amino acid sequences within the alpha subunit of integrin alpha M beta 2 (Mac-1) critical for specific recognition of C3bi.

Authors:  L Zhang; E F Plow
Journal:  Biochemistry       Date:  1999-06-22       Impact factor: 3.162

7.  Solvent-accessible residues on the metal ion-dependent adhesion site face of integrin CR3 mediate its binding to the neutrophil inhibitory factor.

Authors:  P Rieu; T Sugimori; D L Griffith; M A Arnaout
Journal:  J Biol Chem       Date:  1996-07-05       Impact factor: 5.157

8.  LFA-1 is sufficient in mediating neutrophil emigration in Mac-1-deficient mice.

Authors:  H Lu; C W Smith; J Perrard; D Bullard; L Tang; S B Shappell; M L Entman; A L Beaudet; C M Ballantyne
Journal:  J Clin Invest       Date:  1997-03-15       Impact factor: 14.808

9.  Fibrinogen activates NF-kappa B transcription factors in mononuclear phagocytes.

Authors:  R G Sitrin; P M Pan; S Srikanth; R F Todd
Journal:  J Immunol       Date:  1998-08-01       Impact factor: 5.422

10.  Molecular determinants of acute inflammatory responses to biomaterials.

Authors:  L Tang; T P Ugarova; E F Plow; J W Eaton
Journal:  J Clin Invest       Date:  1996-03-01       Impact factor: 14.808
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  12 in total

1.  Leukocyte integrin signaling regulates FOXP1 gene expression via FOXP1-IT1 long non-coding RNA-mediated IRAK1 pathway.

Authors:  Can Shi; Jessica Miley; Alison Nottingham; Toshifumi Morooka; Domenick A Prosdocimo; Daniel I Simon
Journal:  Biochim Biophys Acta Gene Regul Mech       Date:  2019-03-02       Impact factor: 4.490

2.  Peptide ligand structure and I-Aq binding avidity influence T cell signaling pathway utilization.

Authors:  Linda K Myers; David L Cullins; Jeoung-Eun Park; Ae-Kyung Yi; David D Brand; Edward F Rosloniec; John M Stuart; Andrew H Kang
Journal:  Clin Immunol       Date:  2015-05-14       Impact factor: 3.969

3.  Molecular basis for T cell response induced by altered peptide ligand of type II collagen.

Authors:  Jeoung-Eun Park; David Cullins; Lillian Zalduondo; Stacey L Barnett; Ae-Kyung Yi; Sandra Kleinau; John M Stuart; Andrew H Kang; Linda K Myers
Journal:  J Biol Chem       Date:  2012-04-16       Impact factor: 5.157

4.  Antagonism of CD11b with neutrophil inhibitory factor (NIF) inhibits vascular lesions in diabetic retinopathy.

Authors:  Alexander A Veenstra; Jie Tang; Timothy S Kern
Journal:  PLoS One       Date:  2013-10-21       Impact factor: 3.240

5.  Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα.

Authors:  Yunmei Wang; Huiyun Gao; Can Shi; Paul W Erhardt; Alexander Pavlovsky; Dmitry A Soloviev; Kamila Bledzka; Valentin Ustinov; Liang Zhu; Jun Qin; Adam D Munday; Jose Lopez; Edward Plow; Daniel I Simon
Journal:  Nat Commun       Date:  2017-05-30       Impact factor: 14.919

Review 6.  Structural Immunology of Complement Receptors 3 and 4.

Authors:  Thomas Vorup-Jensen; Rasmus Kjeldsen Jensen
Journal:  Front Immunol       Date:  2018-11-26       Impact factor: 7.561

Review 7.  Can Integrin Agonists Have Cards to Play against Cancer? A Literature Survey of Small Molecules Integrin Activators.

Authors:  Alessandra Tolomelli; Paola Galletti; Monica Baiula; Daria Giacomini
Journal:  Cancers (Basel)       Date:  2017-07-05       Impact factor: 6.639

Review 8.  CD40L and Its Receptors in Atherothrombosis-An Update.

Authors:  Nathaly Anto Michel; Andreas Zirlik; Dennis Wolf
Journal:  Front Cardiovasc Med       Date:  2017-06-20

9.  A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense.

Authors:  Dennis Wolf; Nathaly Anto-Michel; Hermann Blankenbach; Ansgar Wiedemann; Konrad Buscher; Jan David Hohmann; Bock Lim; Marina Bäuml; Alex Marki; Maximilian Mauler; Daniel Duerschmied; Zhichao Fan; Holger Winkels; Daniel Sidler; Philipp Diehl; Dirk M Zajonc; Ingo Hilgendorf; Peter Stachon; Timoteo Marchini; Florian Willecke; Maximilian Schell; Björn Sommer; Constantin von Zur Muhlen; Jochen Reinöhl; Teresa Gerhardt; Edward F Plow; Valentin Yakubenko; Peter Libby; Christoph Bode; Klaus Ley; Karlheinz Peter; Andreas Zirlik
Journal:  Nat Commun       Date:  2018-02-06       Impact factor: 14.919

10.  Evidence for functional selectivity in TUDC- and norUDCA-induced signal transduction via α5β1 integrin towards choleresis.

Authors:  Michele Bonus; Annika Sommerfeld; Natalia Qvartskhava; Boris Görg; Beatrice Stefanie Ludwig; Horst Kessler; Holger Gohlke; Dieter Häussinger
Journal:  Sci Rep       Date:  2020-04-02       Impact factor: 4.379
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