Literature DB >> 22075568

Metal to ligand charge transfer induced DNA photobinding in a Ru(II)-Pt(II) supramolecule using red light in the therapeutic window: a new mechanism for DNA modification.

Samantha L H Higgins1, Allison J Tucker, Brenda S J Winkel, Karen J Brewer.   

Abstract

The Ru(II)-Pt(II) supramolecular complex, [(Ph(2)phen)(2)Ru(dpp)PtCl(2)](2+), displays a new mechanism for DNA modification: photobinding through a (3)MLCT excited state. Gel shift analysis, selective DNA precipitation, and DNA melting point experiments support efficient covalent DNA binding following visible light excitation. This journal is © The Royal Society of Chemistry 2012

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Year:  2011        PMID： 22075568     DOI： 10.1039/c1cc15780a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  An Overview Of Photosubstitution Reactions Of Ru(II) Imine Complexes And Their Application In Photobiology And Photodynamic Therapy.

Authors:  Jessica K White; Russell H Schmehl; Claudia Turro
Journal:  Inorganica Chim Acta       Date:  2016-06-18       Impact factor: 2.545

2.  Photochemical and Photobiological Activity of Ru(II) Homoleptic and Heteroleptic Complexes Containing Methylated Bipyridyl-type Ligands.

Authors:  Lars Kohler; Leona Nease; Pascal Vo; Jenna Garofolo; David K Heidary; Randolph P Thummel; Edith C Glazer
Journal:  Inorg Chem       Date:  2017-09-26       Impact factor: 5.165

3.  Preliminary anti-cancer photodynamic therapeutic in vitro studies with mixed-metal binuclear ruthenium(II)-vanadium(IV) complexes.

Authors:  Alvin A Holder; Patrick Taylor; Anthony R Magnusen; Erick T Moffett; Kyle Meyer; Yiling Hong; Stuart E Ramsdale; Michelle Gordon; Javelyn Stubbs; Luke A Seymour; Dhiraj Acharya; Ralph T Weber; Paul F Smith; G Charles Dismukes; Ping Ji; Laura Menocal; Fengwei Bai; Jennie L Williams; Donald M Cropek; William L Jarrett
Journal:  Dalton Trans       Date:  2013-09-07       Impact factor: 4.390

4.  Rapid screening of photoactivatable metallodrugs: photonic crystal fibre microflow reactor coupled to ESI mass spectrometry.

Authors:  Ruth J McQuitty; Sarah Unterkofler; Tijmen G Euser; Philip St J Russell; Peter J Sadler
Journal:  RSC Adv       Date:  2017-07-26       Impact factor: 3.361
  4 in total

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