Literature DB >> 22073496

The impact of pharmacogenetics in the treatment of allergic disease and asthma.

Bridgette L Jones1.   

Abstract

Personalized medicine includes the application of genomic information in predicting disease and therapeutic response to ultimately individualize patient care. Pharmacogenetics is key in achieving true personalized care. However, the clinical applicability of genetic testing to "everyday medicine" is yet to be realized. This paper will discuss areas in allergic/inflammatory disease that have been impacted by pharmacogenetic research and how this application may be brought from the "bench to the bedside."

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Year:  2011        PMID： 22073496      PMCID： PMC6188382     

Source DB:  PubMed          Journal:  Mo Med        ISSN： 0026-6620


  25 in total

1.  Effects of montelukast and beclomethasone on airway function and asthma control.

Authors:  Elliot Israel; Paul S Chervinsky; Bruce Friedman; Julius Van Bavel; Carol S Skalky; Asma F Ghannam; Steven R Bird; Jonathan M Edelman
Journal:  J Allergy Clin Immunol       Date:  2002-12       Impact factor: 10.793

2.  beta-Adrenergic receptor polymorphisms and response to salmeterol.

Authors:  Michael E Wechsler; Erik Lehman; Stephen C Lazarus; Robert F Lemanske; Homer A Boushey; Aaron Deykin; John V Fahy; Christine A Sorkness; Vernon M Chinchilli; Timothy J Craig; Emily DiMango; Monica Kraft; Frank Leone; Richard J Martin; Stephen P Peters; Stanley J Szefler; Wenlei Liu; Elliot Israel
Journal:  Am J Respir Crit Care Med       Date:  2005-12-01       Impact factor: 21.405

3.  Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.

Authors:  Celeste B L Man; Patrick Kwan; Larry Baum; Evelyn Yu; K M Lau; Alice S H Cheng; Margaret H L Ng
Journal:  Epilepsia       Date:  2007-05       Impact factor: 5.864

4.  Warfarin genotyping reduces hospitalization rates results from the MM-WES (Medco-Mayo Warfarin Effectiveness study).

Authors:  Robert S Epstein; Thomas P Moyer; Ronald E Aubert; Dennis J O Kane; Fang Xia; Robert R Verbrugge; Brian F Gage; J Russell Teagarden
Journal:  J Am Coll Cardiol       Date:  2010-04-08       Impact factor: 24.094

5.  Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment.

Authors:  J M Drazen; C N Yandava; L Dubé; N Szczerback; R Hippensteel; A Pillari; E Israel; N Schork; E S Silverman; D A Katz; J Drajesk
Journal:  Nat Genet       Date:  1999-06       Impact factor: 38.330

6.  The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol.

Authors:  Harold S Nelson; Scott T Weiss; Eugene R Bleecker; Steven W Yancey; Paul M Dorinsky
Journal:  Chest       Date:  2006-01       Impact factor: 9.410

7.  Association analysis of drug metabolizing enzyme gene polymorphisms in HIV-positive patients with co-trimoxazole hypersensitivity.

Authors:  M Pirmohamed; A Alfirevic; J Vilar; A Stalford; E G Wilkins; E Sim; B K Park
Journal:  Pharmacogenetics       Date:  2000-11

8.  Genetic variations in HLA-B region and hypersensitivity reactions to abacavir.

Authors:  Seth Hetherington; Arlene R Hughes; Michael Mosteller; Denise Shortino; Katherine L Baker; William Spreen; Eric Lai; Kirstie Davies; Abigail Handley; David J Dow; Mary E Fling; Michael Stocum; Clive Bowman; Linda M Thurmond; Allen D Roses
Journal:  Lancet       Date:  2002-03-30       Impact factor: 79.321

9.  Characterization of within-subject responses to fluticasone and montelukast in childhood asthma.

Authors:  Stanley J Szefler; Brenda R Phillips; Fernando D Martinez; Vernon M Chinchilli; Robert F Lemanske; Robert C Strunk; Robert S Zeiger; Gary Larsen; Joseph D Spahn; Leonard B Bacharier; Gordon R Bloomberg; Theresa W Guilbert; Gregory Heldt; Wayne J Morgan; Mark H Moss; Christine A Sorkness; Lynn M Taussig
Journal:  J Allergy Clin Immunol       Date:  2005-02       Impact factor: 10.793

10.  ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts.

Authors:  Augusto A Litonjua; Jessica Lasky-Su; Kady Schneiter; Kelan G Tantisira; Ross Lazarus; Barbara Klanderman; John J Lima; Charles G Irvin; Stephen P Peters; John P Hanrahan; Stephen B Liggett; Gregory A Hawkins; Deborah A Meyers; Eugene R Bleecker; Christoph Lange; Scott T Weiss
Journal:  Am J Respir Crit Care Med       Date:  2008-07-10       Impact factor: 21.405
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