Literature DB >> 22071525

Recent advances in the biology and chemistry of the flavaglines.

Nigel Ribeiro1, Frédéric Thuaud, Canan Nebigil, Laurent Désaubry.   

Abstract

The flavaglines are a family of plant natural products that induce potent anticancer and neuroprotective activities. This review summarizes recent synthetic approaches to flavaglines and the current status of their pharmacological properties. Copyright Â
© 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 22071525     DOI： 10.1016/j.bmc.2011.10.048

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  21 in total

1.  Enantioselective photocycloaddition of 3-hydroxyflavones: total syntheses and absolute configuration assignments of (+)-ponapensin and (+)-elliptifoline.

Authors:  Neil J Lajkiewicz; Stéphane P Roche; Baudouin Gerard; John A Porco
Journal:  J Am Chem Soc       Date:  2012-07-25       Impact factor: 15.419

Review 2.  Rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species.

Authors:  Li Pan; John L Woodard; David M Lucas; James R Fuchs; A Douglas Kinghorn
Journal:  Nat Prod Rep       Date:  2014-05-02       Impact factor: 13.423

3.  Flavaglines Ameliorate Experimental Colitis and Protect Against Intestinal Epithelial Cell Apoptosis and Mitochondrial Dysfunction.

Authors:  Jie Han; Qian Zhao; Christine Basmadjian; Laurent Désaubry; Arianne L Theiss
Journal:  Inflamm Bowel Dis       Date:  2016-01       Impact factor: 5.325

4.  Chinese herb derived-Rocaglamide A is a potent inhibitor of pancreatic cancer cells.

Authors:  Baochun Wang; Yixiong Li; Fengbo Tan; Zhanxiang Xiao
Journal:  Am J Transl Res       Date:  2016-02-15       Impact factor: 4.060

5.  Amidino-Rocaglates: A Potent Class of eIF4A Inhibitors.

Authors:  Jennifer Chu; Wenhan Zhang; Regina Cencic; William G Devine; Dmitri Beglov; Thomas Henkel; Lauren E Brown; Sandor Vajda; John A Porco; Jerry Pelletier
Journal:  Cell Chem Biol       Date:  2019-09-10       Impact factor: 8.116

6.  Intercepted Retro-Nazarov Reaction: Syntheses of Amidino-Rocaglate Derivatives and Their Biological Evaluation as eIF4A Inhibitors.

Authors:  Wenhan Zhang; Jennifer Chu; Andrew M Cyr; Han Yueh; Lauren E Brown; Tony T Wang; Jerry Pelletier; John A Porco
Journal:  J Am Chem Soc       Date:  2019-07-30       Impact factor: 15.419

7.  Cyclopenta[b]benzofuran and Secodammarane Derivatives from the Stems of Aglaia stellatopilosa.

Authors:  Nuraqilah Othman; Li Pan; Michele Mejin; Julian C L Voong; Hee-byung Chai; Caroline M Pannell; A Douglas Kinghorn; Tiong C Yeo
Journal:  J Nat Prod       Date:  2016-03-14       Impact factor: 4.050

8.  Synthesis of Aza-Rocaglates via ESIPT-Mediated (3+2) Photocycloaddition.

Authors:  Wenyu Wang; Regina Cencic; Luke Whitesell; Jerry Pelletier; John A Porco
Journal:  Chemistry       Date:  2016-07-15       Impact factor: 5.236

9.  A nucleotide signature for identification of Aglaia stellatopilosa Pannell.

Authors:  Belinda Ling Nah Ng; Mariani Omarzuki; Gilbert Sei Kung Lau; Caroline M Pannell; Tiong Chia Yeo
Journal:  Mol Biotechnol       Date:  2014-07       Impact factor: 2.695

10.  Bioactive flavaglines and other constituents isolated from Aglaia perviridis.

Authors:  Li Pan; Ulyana Muñoz Acuña; Jie Li; Nivedita Jena; Tran Ngoc Ninh; Caroline M Pannell; Heebyung Chai; James R Fuchs; Esperanza J Carcache de Blanco; Djaja D Soejarto; A Douglas Kinghorn
Journal:  J Nat Prod       Date:  2013-01-09       Impact factor: 4.050
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