Literature DB >> 2206955

Urinary epidermal growth factor (hEGF) levels in patients with carcinomas of the breast, colon and rectum.

J W Sweetenham1, D E Davies, S Warnes, P Alexander.   

Abstract

A specific two-site ELISA for human epidermal growth factor (hEGF) has been used to measure urinary hEGF/creatinine ratios in 30 normal subjects, 30 hospital in-patients with breast cancer and 30 hospital in-patients with colonic or rectal cancer. There was no significant difference between patients with breast cancer and controls. Although a statistically significant difference between patients with colorectal cancer and controls was observed, the biological significance of this observation is doubtful. No clear effect of the presence of breast or colorectal carcinoma on the urinary excretion of hEGF has been observed.

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Year:  1990        PMID： 2206955      PMCID： PMC1971436          DOI： 10.1038/bjc.1990.318

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  14 in total

1.  Simple, rapid, kinetic method for serum creatinine measurement.

Authors:  J A Lustgarten; R E Wenk
Journal:  Clin Chem       Date:  1972-11       Impact factor: 8.327

2.  Urogastrone levels in the urine of normal adult humans.

Authors:  H Gregory; J E Holmes; I R Willshire
Journal:  J Clin Endocrinol Metab       Date:  1977-10       Impact factor: 5.958

3.  Homologous radioimmunoassay for human epidermal growth factor (urogastrone).

Authors:  G E Dailey; J W Kraus; D N Orth
Journal:  J Clin Endocrinol Metab       Date:  1978-06       Impact factor: 5.958

4.  Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences.

Authors:  J Downward; Y Yarden; E Mayes; G Scrace; N Totty; P Stockwell; A Ullrich; J Schlessinger; M D Waterfield
Journal:  Nature       Date:  1984 Feb 9-15       Impact factor: 49.962

5.  Urinary excretion of human epidermal growth factor (hEGF) in patients with malignant tumors.

Authors:  M Uchihashi; Y Hirata; H Nakajima; T Fujita; S Matsukura
Journal:  Horm Metab Res       Date:  1983-05       Impact factor: 2.936

6.  Epidermal growth factor in human urine from birth to puberty.

Authors:  A L Mattila; J Perheentupa; K Pesonen; L Viinikka
Journal:  J Clin Endocrinol Metab       Date:  1985-11       Impact factor: 5.958

7.  Mouse prepro-epidermal growth factor synthesis by the kidney and other tissues.

Authors:  L B Rall; J Scott; G I Bell; R J Crawford; J D Penschow; H D Niall; J P Coghlan
Journal:  Nature       Date:  1985 Jan 17-23       Impact factor: 49.962

8.  Human urinary epidermal growth factor: effects of age, sex and female endocrine status.

Authors:  A L Mattila
Journal:  Life Sci       Date:  1986-11-17       Impact factor: 5.037

9.  Epidermal growth factor gene expression is regulated differently in mouse kidney and submandibular gland.

Authors:  R M Gubits; P A Shaw; E W Gresik; A Onetti-Muda; T Barka
Journal:  Endocrinology       Date:  1986-09       Impact factor: 4.736

10.  Assessment by a two-site enzyme immunoassay of human epidermal growth factor (urogastrone) in the urine of patients with various gastrointestinal diseases including malignant tumors.

Authors:  M Kurobe; M Aono; M Moriga; S Furukawa; K Hayashi
Journal:  Biochem Int       Date:  1985-12
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  1 in total

1.  Immunoreactive low-molecular-weight epidermal growth factor in urine of patients with renal cell carcinoma.

Authors:  P le Coutre; S Bock; G Jakse; P E Petrides
Journal:  Urol Res       Date:  1992
  1 in total

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