Literature DB >> 22068655

MAGE: the spell is broken.

Katayoun Rezvani.   

Abstract

The success of immunotherapy in Hodgkin lymphoma is hampered partly by limited expression of tumor-specific antigens in the malignant cells. One strategy to increase tumor immunogenicity may be to enhance the expression of Hodgkin lymphoma-specific antigens such as MAGE-A4 using epigenetic-modifying drugs in combination with cancer testis antigen-specific immunotherapy.

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Year:  2011        PMID: 22068655     DOI: 10.1158/1078-0432.CCR-11-2302

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN: 1078-0432            Impact factor:   12.531


  1 in total

1.  Induction of a specific CD8+ T-cell response to cancer/testis antigens by demethylating pre-treatment against osteosarcoma.

Authors:  Binghao Li; Xiaobing Zhu; Lingling Sun; Li Yuan; Jian Zhang; Hengyuan Li; Zhaoming Ye
Journal:  Oncotarget       Date:  2014-11-15
  1 in total

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