BACKGROUND: Infections caused by extended-spectrum β-lactamase (ESBL)-producing bacteria become an emerging problem in the community setting in many parts of the world. OBJECTIVE: The objective of the study was to determine fecal carriage of ESBL-producing organisms in a community setting. METHODS: A total of 632 fecal specimens from healthy individuals were screened for ESBL using the agar screening test with MacConkey agar plates supplemented with 1 μg/mL of cefotaxime for selection of ESBL-producing strains and confirmed by the Clinical Laboratory Standards Institute combined disk method. RESULTS: Four hundred isolates (63.3%) were ESBL producers. Two hundred eighty-five isolates (71.25%) of them were Escherichia coli and 96 (24.0%) Klebsiella pneumoniae. CONCLUSION: We concluded that the community could be a reservoir of these ESBL-producing bacteria and enzymes.
BACKGROUND: Infections caused by extended-spectrum β-lactamase (ESBL)-producing bacteria become an emerging problem in the community setting in many parts of the world. OBJECTIVE: The objective of the study was to determine fecal carriage of ESBL-producing organisms in a community setting. METHODS: A total of 632 fecal specimens from healthy individuals were screened for ESBL using the agar screening test with MacConkey agar plates supplemented with 1 μg/mL of cefotaxime for selection of ESBL-producing strains and confirmed by the Clinical Laboratory Standards Institute combined disk method. RESULTS: Four hundred isolates (63.3%) were ESBL producers. Two hundred eighty-five isolates (71.25%) of them were Escherichia coli and 96 (24.0%) Klebsiella pneumoniae. CONCLUSION: We concluded that the community could be a reservoir of these ESBL-producing bacteria and enzymes.
Authors: Scott A Weisenberg; Jose R Mediavilla; Liang Chen; Elizabeth L Alexander; Kyu Y Rhee; Barry N Kreiswirth; Stephen G Jenkins Journal: PLoS One Date: 2012-09-20 Impact factor: 3.240
Authors: Joshua T Freeman; Joseph Rubin; Gary N McAuliffe; Gisele Peirano; Sally A Roberts; Dragana Drinković; Johann Dd Pitout Journal: Antimicrob Resist Infect Control Date: 2014-09-01 Impact factor: 4.887
Authors: N S Fam; S Defasque; F Bert; V Leflon-Guibout; A El-Ray; M El-Ghannam; M E Attia; M Omar; D G Desouki; D Valla; M-H Nicolas-Chanoine Journal: Epidemiol Infect Date: 2014-07-18 Impact factor: 4.434