Literature DB >> 22067710

mTOR in podocyte function: is rapamycin good for diabetic nephropathy?

Min-Kan Lu, Xing-Guo Gong, Kun-Liang Guan.   

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Year:  2011        PMID： 22067710      PMCID： PMC3266173          DOI： 10.4161/cc.10.20.17686

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  5 in total

1.  Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.

Authors:  Markus Gödel; Björn Hartleben; Nadja Herbach; Shuya Liu; Stefan Zschiedrich; Shun Lu; Andrea Debreczeni-Mór; Maja T Lindenmeyer; Maria-Pia Rastaldi; Götz Hartleben; Thorsten Wiech; Alessia Fornoni; Robert G Nelson; Matthias Kretzler; Rüdiger Wanke; Hermann Pavenstädt; Dontscho Kerjaschki; Clemens D Cohen; Michael N Hall; Markus A Rüegg; Ken Inoki; Gerd Walz; Tobias B Huber
Journal:  J Clin Invest       Date:  2011-05-23       Impact factor: 14.808

2.  mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.

Authors:  Ken Inoki; Hiroyuki Mori; Junying Wang; Tsukasa Suzuki; SungKi Hong; Sei Yoshida; Simone M Blattner; Tsuneo Ikenoue; Markus A Rüegg; Michael N Hall; David J Kwiatkowski; Maria P Rastaldi; Tobias B Huber; Matthias Kretzler; Lawrence B Holzman; Roger C Wiggins; Kun-Liang Guan
Journal:  J Clin Invest       Date:  2011-05-23       Impact factor: 14.808

Review 3.  Need for better diabetes treatment for improved renal outcome.

Authors:  Peter Rossing; Dick de Zeeuw
Journal:  Kidney Int Suppl       Date:  2011-03       Impact factor: 10.545

Review 4.  mTOR: from growth signal integration to cancer, diabetes and ageing.

Authors:  Roberto Zoncu; Alejo Efeyan; David M Sabatini
Journal:  Nat Rev Mol Cell Biol       Date:  2010-12-15       Impact factor: 94.444

Review 5.  Cell biology of the glomerular podocyte.

Authors:  Hermann Pavenstädt; Wilhelm Kriz; Matthias Kretzler
Journal:  Physiol Rev       Date:  2003-01       Impact factor: 37.312
  5 in total
  16 in total

1.  In vitro and in vivo inhibition of mTOR by 1,25-dihydroxyvitamin D3 to improve early diabetic nephropathy via the DDIT4/TSC2/mTOR pathway.

Authors:  Hang Wang; Jianmin Wang; Hua Qu; Huili Wei; Baolan Ji; Zesong Yang; Jing Wu; Qin He; Yuanyuan Luo; Dan Liu; Yang Duan; Fang Liu; Huacong Deng
Journal:  Endocrine       Date:  2016-07-09       Impact factor: 3.633

2.  Rapamycin promotes podocyte autophagy and ameliorates renal injury in diabetic mice.

Authors:  Tangli Xiao; Xu Guan; Ling Nie; Song Wang; Lei Sun; Ting He; Yunjian Huang; Jingbo Zhang; Ke Yang; Junping Wang; Jinghong Zhao
Journal:  Mol Cell Biochem       Date:  2014-05-22       Impact factor: 3.396

Review 3.  Insights into the Mechanisms Involved in the Expression and Regulation of Extracellular Matrix Proteins in Diabetic Nephropathy.

Authors:  C Hu; L Sun; L Xiao; Y Han; X Fu; X Xiong; X Xu; Y Liu; S Yang; F Liu; Y S Kanwar
Journal:  Curr Med Chem       Date:  2015       Impact factor: 4.530

Review 4.  The role of extracellular vesicles in podocyte autophagy in kidney disease.

Authors:  Baichao Sun; Shubo Zhai; Li Zhang; Guangdong Sun
Journal:  J Cell Commun Signal       Date:  2021-02-22       Impact factor: 5.782

Review 5.  Once again on rapamycin-induced insulin resistance and longevity: despite of or owing to.

Authors:  Mikhail V Blagosklonny
Journal:  Aging (Albany NY)       Date:  2012-05       Impact factor: 5.682

Review 6.  Research Progress on Mechanism of Podocyte Depletion in Diabetic Nephropathy.

Authors:  Haoran Dai; Qingquan Liu; Baoli Liu
Journal:  J Diabetes Res       Date:  2017-07-16       Impact factor: 4.011

7.  Reversal of Early Diabetic Nephropathy by Islet Transplantation under the Kidney Capsule in a Rat Model.

Authors:  Yunqiang He; Ziqiang Xu; Mingshi Zhou; Minmin Wu; Xuehai Chen; Silu Wang; Kaiyan Qiu; Yong Cai; Hongxing Fu; Bicheng Chen; Mengtao Zhou
Journal:  J Diabetes Res       Date:  2016-09-20       Impact factor: 4.011

8.  Mechanistic or mammalian target of rapamycin (mTOR) may determine robustness in young male mice at the cost of accelerated aging.

Authors:  Olga V Leontieva; Geraldine M Paszkiewicz; Mikhail V Blagosklonny
Journal:  Aging (Albany NY)       Date:  2012-12       Impact factor: 5.682

Review 9.  Answering the ultimate question "what is the proximal cause of aging?".

Authors:  Mikhail V Blagosklonny
Journal:  Aging (Albany NY)       Date:  2012-12       Impact factor: 5.682

Review 10.  Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance.

Authors:  James A McCubrey; Linda S Steelman; William H Chappell; Stephen L Abrams; Richard A Franklin; Giuseppe Montalto; Melchiorre Cervello; Massimo Libra; Saverio Candido; Grazia Malaponte; Maria C Mazzarino; Paolo Fagone; Ferdinando Nicoletti; Jörg Bäsecke; Sanja Mijatovic; Danijela Maksimovic-Ivanic; Michele Milella; Agostino Tafuri; Francesca Chiarini; Camilla Evangelisti; Lucio Cocco; Alberto M Martelli
Journal:  Oncotarget       Date:  2012-10
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