| Literature DB >> 220673 |
C Omini, G C Folco, R Pasargiklian, M Fano, F Berti.
Abstract
Prostacyclin lowers the tonus and reduces the spontaneous motility of isolated pregnant human myometrium. This effect seems to be related to coclic-AMP accumulation, since PGI2 increases the formation of this cyclic nucleotide in incubated minces of pregnant and non-pregnant uterus. The ability of this tissue to generate a labile substance which inhibits platelets aggregation, has been demonstrated and discussed.Entities:
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Year: 1979 PMID： 220673 DOI： 10.1016/0090-6980(79)90082-0
Source DB: PubMed Journal: Prostaglandins ISSN： 0090-6980