Literature DB >> 22066362

Functional tricuspid valve regurgitation in adults with congenital heart disease: an emerging problem.

Alessandro Giamberti1, Massimo Chessa, Andrea Ballotta, Alessandro Varrica, Aldo Agnetti, Alessandro Frigiola, Marco Ranucci.   

Abstract

BACKGROUND AND AIM OF THE STUDY: At present, limited data are available regarding functional tricuspid regurgitation (TR) in adults with congenital heart disease (ACHD). Functional TR is the consequence of right ventricular (RV) dilation or dysfunction that, in these patients, is typically associated with chronic RV volume overloading. The study aim was to resolve this problem by evaluating results obtained from patients after surgical treatment of ACHD.
METHODS: A total of 65 patients (mean age 46 years) with ACHD underwent an operation to correct functional TR during elective cardiac surgery between January 2000 and December 2008 at the authors' institution. The preoperative median NYHA functional class was 3, and the median TR grade was 3. Surgical treatment of the primary cardiac lesion included atrial septal defect (ASD) closure in 40 patients and pulmonary valve implantation in 25. Functional TR was treated by annuloplasty (n = 48), rigid tricuspid valve ring (n = 14), or tricuspid valve replacement (n = 3).
RESULTS: There were no in-hospital deaths. The median TR grade at discharge was 0. During a mean follow up period of 63 months (range: 12-96 months) there was one delayed death that was not cardiac-related. Both, the NYHA functional class (p = 0.001) and TR grade (p = 0.001) were significantly improved among survivors. One patient (1.5%) had tricuspid valve replacement at five years after annuloplasty. No significant differences regarding annuloplasty versus rigid tricuspid valve ring were noted during the follow up period.
CONCLUSION: Functional TR is an emerging, though as yet still underestimated, problem in ACHD. It is a consequence of RV dilation/dysfunction that, in these patients, is typically related to chronic RV volume overloading. Surgery should be considered to resolve this problem, and can be performed at low risk and with good mid-term results.

Entities:  

Mesh:

Year:  2011        PMID: 22066362

Source DB:  PubMed          Journal:  J Heart Valve Dis        ISSN: 0966-8519


  7 in total

Review 1.  Tricuspid regurgitation: pathophysiology and management.

Authors:  Rashmi Thapa; Buddhadeb Dawn; Jayant Nath
Journal:  Curr Cardiol Rep       Date:  2012-04       Impact factor: 2.931

Review 2.  Evidence-based surgical management of acquired tricuspid valve disease.

Authors:  Sung Ho Shinn; Hartzell V Schaff
Journal:  Nat Rev Cardiol       Date:  2013-02-12       Impact factor: 32.419

3.  The care for adults with congenital heart disease: organization and function of a grown-up congenital heart disease unit.

Authors:  Alessandro Giamberti; Alessandro Varrica; Giuseppe Pomè; Angelo Micheletti; Diana Negura; Marco Ranucci; Mario Carminati; Alessandro Frigiola; Massimo Chessa
Journal:  Eur Heart J Suppl       Date:  2016-04-29       Impact factor: 1.803

Review 4.  Is a tricuspid annuloplasty ring significantly better than a De Vega's annuloplasty stitch when repairing severe tricuspid regurgitation?

Authors:  Maziar Khorsandi; Amit Banerjee; Harpreet Singh; Aseem R Srivastava
Journal:  Interact Cardiovasc Thorac Surg       Date:  2012-03-28

5.  Normalization of the right heart and the preoperative factors that influence the emergence PAH after surgical closure of atrial septal defect.

Authors:  Supomo Supomo; Agung Widhinugroho; Aditya Agam Nugraha
Journal:  J Cardiothorac Surg       Date:  2020-05-20       Impact factor: 1.637

6.  Early onset of cyanosis in a patient with atrial septal defect: Transesophageal echocardiography reveals the underlying mechanism.

Authors:  Rohan Magoon; Arindam Choudhury; Ameya Karanjkar; Ummed Singh
Journal:  Ann Card Anaesth       Date:  2018 Jul-Sep

7.  Surgery for Functional Tricuspid Regurgitation in Adult Atrial Septal Defect - An Increasing Subject in a Decreasing Matter.

Authors:  Andrei George Iosifescu; Alexandru Popescu; Toma Andrei Iosifescu; Alina Teodora Timişescu; Sorin Maximeasa; Vlad Anton Iliescu
Journal:  Braz J Cardiovasc Surg       Date:  2022-05-23
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.