Literature DB >> 22065941

MicroRNA signatures of stem cells.

Dipak K Das1, Partha Mukhopadhyay.   

Abstract

The unique properties of embryonic stem (ES) cells to self-renew indefinitely or to differentiate to any cell type (pluripotency) warrants their clinical application in regenerative medicine. MicroRNAs are crucial for post-transcriptional gene regulation and, thus, remain an essential element of the regulation of ES cells. The present review discusses the essential elements of microRNAs that regulate the life and death of ES cells.

Keywords:  MicroRNA; MicroRNA biogenesis; MicroRNA-based therapeutics; Redox cycling; Regenerative medicine; Stem cells

Year:  2011        PMID： 22065941      PMCID： PMC3209547     

Source DB:  PubMed          Journal:  Exp Clin Cardiol        ISSN： 1205-6626


  30 in total

1.  A bivalent chromatin structure marks key developmental genes in embryonic stem cells.

Authors:  Bradley E Bernstein; Tarjei S Mikkelsen; Xiaohui Xie; Michael Kamal; Dana J Huebert; James Cuff; Ben Fry; Alex Meissner; Marius Wernig; Kathrin Plath; Rudolf Jaenisch; Alexandre Wagschal; Robert Feil; Stuart L Schreiber; Eric S Lander
Journal:  Cell       Date:  2006-04-21       Impact factor: 41.582

Review 2.  RNAi therapeutics: principles, prospects and challenges.

Authors:  Lars Aagaard; John J Rossi
Journal:  Adv Drug Deliv Rev       Date:  2007-03-16       Impact factor: 15.470

Review 3.  Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming.

Authors:  Rudolf Jaenisch; Richard Young
Journal:  Cell       Date:  2008-02-22       Impact factor: 41.582

4.  MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells.

Authors:  Margaret S Ebert; Joel R Neilson; Phillip A Sharp
Journal:  Nat Methods       Date:  2007-08-12       Impact factor: 28.547

5.  Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430.

Authors:  Wen-Yee Choi; Antonio J Giraldez; Alexander F Schier
Journal:  Science       Date:  2007-08-30       Impact factor: 47.728

Review 6.  MicroRNA signatures of resveratrol in the ischemic heart.

Authors:  Partha Mukhopadhyay; Pal Pacher; Dipak K Das
Journal:  Ann N Y Acad Sci       Date:  2011-01       Impact factor: 5.691

7.  Generation of germline-competent induced pluripotent stem cells.

Authors:  Keisuke Okita; Tomoko Ichisaka; Shinya Yamanaka
Journal:  Nature       Date:  2007-06-06       Impact factor: 49.962

8.  MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation.

Authors:  Jian Huang; Lan Zhao; Lianping Xing; Di Chen
Journal:  Stem Cells       Date:  2010-02       Impact factor: 6.277

9.  Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms.

Authors:  Carlos M Loya; Cecilia S Lu; David Van Vactor; Tudor A Fulga
Journal:  Nat Methods       Date:  2009-11-15       Impact factor: 28.547

10.  Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver.

Authors:  Joacim Elmén; Morten Lindow; Asli Silahtaroglu; Mads Bak; Mette Christensen; Allan Lind-Thomsen; Maj Hedtjärn; Jens Bo Hansen; Henrik Frydenlund Hansen; Ellen Marie Straarup; Keith McCullagh; Phil Kearney; Sakari Kauppinen
Journal:  Nucleic Acids Res       Date:  2007-12-23       Impact factor: 16.971
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