Literature DB >> 22065804

Worth syndrome as a diagnosis for mandibular osteosclerosis.

K Payne1, A Dickenson.   

Abstract

This case report presents an unusual incidental radiographic finding on a dental panoramic radiograph that caused diagnostic confusion. A 46-year-old female presented with symmetrical sclerotic cortical thickening of the anterior mandible visible on radiograph, with no other major clinical examination findings. The patient subsequently showed no change in radiographic appearance over a 6 year period. Based on this evidence, and the benign nature of the history, we propose a diagnosis of Worth syndrome. This report aims to clarify the difference in terminology and presentation of two conditions known to produce mandibular osteosclerosis: Worth syndrome and Van Buchem disease, both of which are often quoted synonymously in the literature.

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Mesh:

Year:  2011        PMID: 22065804      PMCID: PMC3528158          DOI: 10.1259/dmfr/71865631

Source DB:  PubMed          Journal:  Dentomaxillofac Radiol        ISSN: 0250-832X            Impact factor:   2.419


  7 in total

1.  Hyperostosis corticalis generalisata congenita.

Authors:  H M Worth; D G Wollin
Journal:  J Can Assoc Radiol       Date:  1966-06

2.  Hyperostosis corticalis generalisata: surgical management and long-term follow-up of one patient.

Authors:  Y Marmary; T Horne; B Azaz
Journal:  Int J Oral Maxillofac Surg       Date:  1989-06       Impact factor: 2.789

3.  Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density.

Authors:  Liesbeth Van Wesenbeeck; Erna Cleiren; Jeppe Gram; Rodney K Beals; Olivier Bénichou; Domenico Scopelliti; Lyndon Key; Tara Renton; Cindy Bartels; Yaoqin Gong; Matthew L Warman; Marie-Christine De Vernejoul; Jens Bollerslev; Wim Van Hul
Journal:  Am J Hum Genet       Date:  2003-02-10       Impact factor: 11.025

4.  Van Buchem disease: surgical treatment of the mandible.

Authors:  S A Schendel
Journal:  Ann Plast Surg       Date:  1988-05       Impact factor: 1.539

5.  Van Buchem disease.

Authors:  P Jacobs
Journal:  Postgrad Med J       Date:  1977-08       Impact factor: 2.401

6.  Autosomal dominant osteosclerosis.

Authors:  R J Gorlin; L Glass
Journal:  Radiology       Date:  1977-11       Impact factor: 11.105

7.  Patients with Van Buchem disease, an osteosclerotic genetic disease, have elevated bone formation markers, higher bone density, and greater derived polar moment of inertia than normal.

Authors:  Jon E Wergedal; Katarina Veskovic; Minea Hellan; Christine Nyght; Wendy Balemans; Cesar Libanati; Filip M Vanhoenacker; Johan Tan; David J Baylink; Wim Van Hul
Journal:  J Clin Endocrinol Metab       Date:  2003-12       Impact factor: 5.958

  7 in total
  1 in total

Review 1.  Worth syndrome "mandibular osteosclerosis" as an incidental finding: a report of 2 cases.

Authors:  Kent S Thompson; Adepitan A Owosho
Journal:  Dentomaxillofac Radiol       Date:  2018-07-20       Impact factor: 2.419

  1 in total

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