Literature DB >> 22064830

Label-free visual detection of nucleic acids in biological samples with single-base mismatch detection capability.

Yanling Song1, Weiting Zhang, Yuan An, Liang Cui, Chundong Yu, Zhi Zhu, Chaoyong James Yang.   

Abstract

We have combined an allosteric molecular beacon for target recognition and guanine-rich DNAzyme for signal amplification to develop a new platform for visual detection of nucleic acids with single-base mismatch detection capability. The fully DNA-structured platform can undergo color change in response to target DNA/RNA, which enables sensitive and selective visual detection in biological samples. This journal is © The Royal Society of Chemistry 2012

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Year:  2011        PMID: 22064830     DOI: 10.1039/c1cc15777a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Ultrasensitive single-nucleotide polymorphism detection using target-recycled ligation, strand displacement and enzymatic amplification.

Authors:  Yue Zhang; Yuan Guo; Philip Quirke; Dejian Zhou
Journal:  Nanoscale       Date:  2013-05-02       Impact factor: 7.790

  1 in total

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