Literature DB >> 22064516

Genetic selection for enhanced serine metabolism in cancer development.

Jason W Locasale, Lewis C Cantley.   

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Year:  2011        PMID： 22064516     DOI： 10.4161/cc.10.22.18224

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  17 in total

1.  Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism.

Authors:  Ryan J Davis; Mehmet Gönen; Daciana H Margineantu; Shlomo Handeli; Jherek Swanger; Pia Hoellerbauer; Patrick J Paddison; Haiwei Gu; Daniel Raftery; Jonathan E Grim; David M Hockenbery; Adam A Margolin; Bruce E Clurman
Journal:  Proc Natl Acad Sci U S A       Date:  2018-05-07       Impact factor: 11.205

2.  Functional and Metabolomic Consequences of KATP Channel Inactivation in Human Islets.

Authors:  Changhong Li; Amanda M Ackermann; Kara E Boodhansingh; Tricia R Bhatti; Chengyang Liu; Jonathan Schug; Nicolai Doliba; Bing Han; Karen E Cosgrove; Indraneel Banerjee; Franz M Matschinsky; Itzhak Nissim; Klaus H Kaestner; Ali Naji; N Scott Adzick; Mark J Dunne; Charles A Stanley; Diva D De León
Journal:  Diabetes       Date:  2017-04-25       Impact factor: 9.461

3.  Small molecule activation of PKM2 in cancer cells induces serine auxotrophy.

Authors:  Charles Kung; Jeff Hixon; Sung Choe; Kevin Marks; Stefan Gross; Erin Murphy; Byron DeLaBarre; Giovanni Cianchetta; Shalini Sethumadhavan; Xiling Wang; Shunqi Yan; Yi Gao; Cheng Fang; Wentao Wei; Fan Jiang; Shaohui Wang; Kevin Qian; Jeff Saunders; Ed Driggers; Hin Koon Woo; Kaiko Kunii; Stuart Murray; Hua Yang; Katharine Yen; Wei Liu; Lewis C Cantley; Matthew G Vander Heiden; Shinsan M Su; Shengfang Jin; Francesco G Salituro; Lenny Dang
Journal:  Chem Biol       Date:  2012-09-21

Review 4.  The ins and outs of serine and glycine metabolism in cancer.

Authors:  Shauni L Geeraerts; Elien Heylen; Kim De Keersmaecker; Kim R Kampen
Journal:  Nat Metab       Date:  2021-01-28

Review 5.  Serine, glycine and one-carbon units: cancer metabolism in full circle.

Authors:  Jason W Locasale
Journal:  Nat Rev Cancer       Date:  2013-07-04       Impact factor: 60.716

6.  Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer.

Authors:  Qi Wang; Prashanth T Bhaskar; Krushna C Patra; Luke Miller; Zebin Wang; Will Wheaton; Navdeep Chandel; Markku Laakso; William J Muller; Eric L Allen; Abhishek K Jha; Gromoslaw A Smolen; Michelle F Clasquin; Brooks Robey; Nissim Hay
Journal:  Cancer Cell       Date:  2013-08-01       Impact factor: 31.743

7.  Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1.

Authors:  Shiwen Wang; Bowen Jiang; Tengfei Zhang; Lixia Liu; Yi Wang; Yiping Wang; Xiufei Chen; Huaipeng Lin; Lisha Zhou; Yukun Xia; Leilei Chen; Chen Yang; Yue Xiong; Dan Ye; Kun-Liang Guan
Journal:  PLoS Biol       Date:  2015-09-10       Impact factor: 8.029

8.  NF-κB, p38 MAPK, ERK1/2, mTOR, STAT3 and increased glycolysis regulate stability of paricalcitol/dexamethasone-generated tolerogenic dendritic cells in the inflammatory environment.

Authors:  Klára Dáňová; Anna Klapetková; Jana Kayserová; Anna Šedivá; Radek Špíšek; Lenka Palová Jelínková
Journal:  Oncotarget       Date:  2015-06-10

Review 9.  Serine and glycine metabolism in cancer.

Authors:  Ivano Amelio; Francesca Cutruzzolá; Alexey Antonov; Massimiliano Agostini; Gerry Melino
Journal:  Trends Biochem Sci       Date:  2014-03-20       Impact factor: 13.807

10.  Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells.

Authors:  Oliver D K Maddocks; Christiaan F Labuschagne; Peter D Adams; Karen H Vousden
Journal:  Mol Cell       Date:  2016-01-07       Impact factor: 17.970
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